Small interfering RNA (siRNA) is a potential method of gene silencing to target specific
genes. Although the US Food and Drug Administration (FDA) has approved multiple siRNA …

Chemotherapy is a key treatment option for gastric cancer, but over 50% of patients develop
either inherent or acquired resistance to these drugs, resulting in a 5-year survival rate of …

Tissue regeneration technology has been rapidly developed and widely applied in tissue
engineering and repair. Compared with traditional approaches like surgical treatment, the …

RNA interference (RNAi) is a major cellular mechanism regulating gene expression in which
short double-stranded RNA molecules called small interfering RNA (siRNA) mediate …

Resistance to antimicrobials and particularly multidrug resistance is one of the greatest
challenges in the health system nowadays. The continual increase in the rates of …

Nanomedicines have gained popularity due to their potential therapeutic applications,
especially cancer treatment. Targeted nanoparticles can deliver drugs directly to cancer …

Cancer has been considered as complex malignant consequence of genetic mutations that
control the cellular proliferation, differentiation and homeostasis, thus making tumor …

Introduction RNA interference (RNAi) using small interfering RNA (siRNA) is a promising
strategy to control many genetic disorders by targeting the mRNA of underlying genes and …

RNA interference has become increasingly used for genetic therapy following the rapid
development of oligonucleotide drugs. Significant progress has been made in its delivery …

The term nanocarrier refers to sub-micrometric particles of less than 100 nm, designed to
transport, distribute, and release nanotechnology-based drug delivery systems. siRNA …