In recent years nanotechnology has revolutionized the healthcare strategies and envisioned
to have a tremendous impact to offer better health facilities. In this context, medical …

Abstract Purpose Helical Tomotherapy (HT) plans were used to create two RapidPlan
knowledge-based (KB) models to generate plans with different techniques and to guide the …

Purpose Changes in fraction size of external beam radiation therapy exert nonlinear effects
on subsequent toxicity. Commonly described by the linear-quadratic model, fraction size …

Methionine is an essential amino acid needed for a variety of processes in living organisms.
Ionizing radiation depletes tissue methionine concentrations and leads to the loss of DNA …

Purpose/objective Assess to what extent the use of automated treatment planning would
have reduced organ-at-risk dose delivery observed in the randomized HYPRO trial for …

Purpose This study aimed to validate a previously published predictive model for late fecal
incontinence (FI) in a contemporary population of prostate cancer patients treated with …

Traditionally rectal symptoms following pelvic/prostate radiotherapy are correlated to the
dosimetry of the anorectum or a substructure of this. It has been suggested that the perirectal …

Purpose To validate published models for the risk estimate of grade≥ 1 (G1+), grade≥ 2
(G2+) and grade= 3 (G3) late rectal bleeding (LRB) after radical radiotherapy for prostate …

Background Radiation-induced organ dysfunction are frequently described by Normal
Tissue Complication Probability models. The approximations of this radiobiological …

A reduction in toxicity is seen in parallel with radiation technological advances such as
image guided intensity modulated radiotherapy. The irradiation field usually encompasses …