Autoantibodies are currently the most robust biomarkers of type 1 diabetes and are
frequently used to establish entry criteria for the participation of genetically at-risk individuals …

Type 1 diabetes (T1D) culminates in the autoimmune destruction of the pancreatic βcells,
leading to insufficient production of insulin and development of hyperglycemia. Serum …

We aim to establish a comprehensive COVID-19 autoantigen atlas in order to understand
autoimmune diseases caused by SARS-CoV-2 infection. Based on the unique affinity …

Breast cancer is a major cause of mortality in women; however, technologies for early stage
screening and diagnosis (eg, mammography and other imaging technologies) are not …

COVID-19 is accompanied by a myriad of both transient and long-lasting autoimmune
responses. Dermatan sulfate (DS), a glycosaminoglycan crucial for wound healing, has …

Chronic and debilitating autoimmune sequelae pose a grave concern for the post-COVID-19
pandemic era. Based on our discovery that the glycosaminoglycan dermatan sulfate (DS) …

Glaucoma is an optic neurological disorder and the leading cause of irreversible blindness
worldwide, with primary open angle glaucoma (POAG) as its most prevalent form. An early …

We performed an unbiased proteome-scale profiling of humoral autoimmunity in recent-
onset type 1 diabetes (T1D) patients and nondiabetic controls against∼ 10 000 human …

Highlights•AAb can be used for cancer early detection, imaging, and therapeutics.•PTMs can
form neoantigens, stimulating autoantibody production.•New high-dimensional techniques …

Background B-cell acute lymphoblastic leukemia (B-ALL) is the most common malignancy of
childhood. Even though significant progresses have been made in the treatment of B-ALL …