Cancer stem cells: advances in knowledge and implications for cancer therapy

X Chu, W Tian, J Ning, G Xiao, Y Zhou… - … and Targeted Therapy, 2024 - nature.com
Cancer stem cells (CSCs), a small subset of cells in tumors that are characterized by self-
renewal and continuous proliferation, lead to tumorigenesis, metastasis, and maintain tumor …

Aspects of the tumor microenvironment involved in immune resistance and drug resistance

K Khalaf, D Hana, JTT Chou, C Singh… - Frontiers in …, 2021 - frontiersin.org
The tumor microenvironment (TME) is a complex and ever-changing “rogue organ”
composed of its own blood supply, lymphatic and nervous systems, stroma, immune cells …

[HTML][HTML] Overcoming Cancer Multi-drug Resistance (MDR): Reasons, mechanisms, nanotherapeutic solutions, and challenges

C Duan, M Yu, J Xu, BY Li, Y Zhao… - Biomedicine & …, 2023 - Elsevier
Multi-drug resistance (MDR) in cancer cells, either intrinsic or acquired through various
mechanisms, significantly hinders the therapeutic efficacy of drugs. Typically, the reduced …

Anti-cancer natural products and their bioactive compounds inducing ER stress-mediated apoptosis: A review

C Kim, B Kim - Nutrients, 2018 - mdpi.com
Cancer is the second biggest cause of death worldwide. Despite a number of studies being
conducted, the effective mechanism for treating cancer has not yet been fully understood …

[HTML][HTML] Chemoresistance mechanisms of breast cancer and their countermeasures

X Ji, Y Lu, H Tian, X Meng, M Wei, WC Cho - Biomedicine & …, 2019 - Elsevier
Chemoresistance is one of the major challenges for the breast cancer treatment. Owing to its
heterogeneous nature, the chemoresistance mechanisms of breast cancer are complicated …

[HTML][HTML] Biomedical applications of supramolecular systems based on host–guest interactions

X Ma, Y Zhao - Chemical reviews, 2015 - ACS Publications
The development of supramolecular chemistry dates back to 1987 when Lehn, Cram, and
Pedersen won the Nobel Prize on account of their leading discoveries in the host–guest …

[HTML][HTML] Broad targeting of resistance to apoptosis in cancer

RM Mohammad, I Muqbil, L Lowe, C Yedjou… - Seminars in cancer …, 2015 - Elsevier
Apoptosis or programmed cell death is natural way of removing aged cells from the body.
Most of the anti-cancer therapies trigger apoptosis induction and related cell death networks …

“Combo” nanomedicine: co-delivery of multi-modal therapeutics for efficient, targeted, and safe cancer therapy

JA Kemp, MS Shim, CY Heo, YJ Kwon - Advanced drug delivery reviews, 2016 - Elsevier
The dynamic and versatile nature of diseases such as cancer has been a pivotal challenge
for developing efficient and safe therapies. Cancer treatments using a single therapeutic …

Plasma for cancer treatment

M Keidar - Plasma Sources Science and Technology, 2015 - iopscience.iop.org
Plasma medicine is a relatively new field that grew from research in application of low-
temperature (or cold) atmospheric plasmas in bioengineering. One of the most promising …

PAMAM dendrimer as a talented multifunctional biomimetic nanocarrier for cancer diagnosis and therapy

B Surekha, NS Kommana, SK Dubey… - Colloids and Surfaces B …, 2021 - Elsevier
Abstract Poly (amidoamine) dendrimers (PAMAM) are novel polymeric highly branched
architectures with well-defined nano-size, narrow polydispersity index and numerous active …