Advances in regenerative stem cell therapy in androgenic alopecia and hair loss: Wnt pathway, growth-factor, and mesenchymal stem cell signaling impact analysis …
P Gentile, S Garcovich - Cells, 2019 - mdpi.com
The use of stem cells has been reported to improve hair regrowth in several therapeutic
strategies, including reversing the pathological mechanisms, that contribute to hair loss …
strategies, including reversing the pathological mechanisms, that contribute to hair loss …
Brain age prediction using deep learning uncovers associated sequence variants
Abstract Machine learning algorithms can be trained to estimate age from brain structural
MRI. The difference between an individual's predicted and chronological age, predicted age …
MRI. The difference between an individual's predicted and chronological age, predicted age …
Ceria nanozyme-integrated microneedles reshape the perifollicular microenvironment for androgenetic alopecia treatment
Androgenetic alopecia (AGA) is highly prevalent in current society but lacks effective
treatments. The dysregulation of the hair follicle niche induced by excessive reactive oxygen …
treatments. The dysregulation of the hair follicle niche induced by excessive reactive oxygen …
Integrated single-cell chromatin and transcriptomic analyses of human scalp identify gene-regulatory programs and critical cell types for hair and skin diseases
B Ober-Reynolds, C Wang, JM Ko, EJ Rios, SZ Aasi… - Nature Genetics, 2023 - nature.com
Genome-wide association studies have identified many loci associated with hair and skin
disease, but identification of causal variants requires deciphering of gene-regulatory …
disease, but identification of causal variants requires deciphering of gene-regulatory …
Hormonal regulation in male androgenetic alopecia—Sex hormones and beyond: Evidence from recent genetic studies
S Heilmann‐Heimbach, LM Hochfeld… - Experimental …, 2020 - Wiley Online Library
Male‐pattern hair loss, also termed androgenetic alopecia (AGA), is a highly prevalent age‐
related condition that is characterized by a distinct pattern of hair loss from the …
related condition that is characterized by a distinct pattern of hair loss from the …
Platelet-rich plasma and micrografts enriched with autologous human follicle mesenchymal stem cells improve hair re-growth in androgenetic alopecia. biomolecular …
P Gentile, MG Scioli, A Bielli, B De Angelis, C De Sio… - Biomedicines, 2019 - mdpi.com
Platelet rich plasma (PRP) and Micrografts containing human follicle mesenchymal stem
cells (HF-MSCs) were tried as a potential treatment for androgenetic alopecia (AGA) …
cells (HF-MSCs) were tried as a potential treatment for androgenetic alopecia (AGA) …
High-coverage genome of the Tyrolean Iceman reveals unusually high Anatolian farmer ancestry
Summary The Tyrolean Iceman is known as one of the oldest human glacier mummies,
directly dated to 3350–3120 calibrated BCE. A previously published low-coverage genome …
directly dated to 3350–3120 calibrated BCE. A previously published low-coverage genome …
Uncovering the complex relationship between balding, testosterone and skin cancers in men
Male-pattern baldness (MPB) is related to dysregulation of androgens such as testosterone.
A previously observed relationship between MPB and skin cancer may be due to greater …
A previously observed relationship between MPB and skin cancer may be due to greater …
Analysis of 72,469 UK Biobank exomes links rare variants to male-pattern hair loss
SK Henne, R Aldisi, S Sivalingam, LM Hochfeld… - Nature …, 2023 - nature.com
Male-pattern hair loss (MPHL) is common and highly heritable. While genome-wide
association studies (GWAS) have generated insights into the contribution of common …
association studies (GWAS) have generated insights into the contribution of common …
Dissection of genetic variation and evidence for pleiotropy in male pattern baldness
Male pattern baldness (MPB) is a sex-limited, age-related, complex trait. We study MPB
genetics in 205,327 European males from the UK Biobank. Here we show that MPB is …
genetics in 205,327 European males from the UK Biobank. Here we show that MPB is …