The cytoskeleton—a complex interacting meshwork

T Hohmann, F Dehghani - Cells, 2019 - mdpi.com
The cytoskeleton of animal cells is one of the most complicated and functionally versatile
structures, involved in processes such as endocytosis, cell division, intra-cellular transport …

Nuclear lamins: thin filaments with major functions

R de Leeuw, Y Gruenbaum, O Medalia - Trends in cell biology, 2018 - cell.com
The nuclear lamina is a nuclear peripheral meshwork that is mainly composed of nuclear
lamins, although a small fraction of lamins also localizes throughout the nucleoplasm …

Microbial decomposition of keratin in nature—a new hypothesis of industrial relevance

L Lange, Y Huang, PK Busk - Applied microbiology and biotechnology, 2016 - Springer
Discovery of keratin-degrading enzymes from fungi and bacteria has primarily focused on
finding one protease with efficient keratinase activity. Recently, an investigation was …

Structure and functions of keratin proteins in simple, stratified, keratinized and cornified epithelia

HH Bragulla, DG Homberger - Journal of anatomy, 2009 - Wiley Online Library
Historically, the term 'keratin'stood for all of the proteins extracted from skin modifications,
such as horns, claws and hooves. Subsequently, it was realized that this keratin is actually a …

Vimentin filaments integrate low-complexity domains in a complex helical structure

M Eibauer, MS Weber, R Kronenberg-Tenga… - Nature Structural & …, 2024 - nature.com
Intermediate filaments (IFs) are integral components of the cytoskeleton. They provide cells
with tissue-specific mechanical properties and are involved in numerous cellular processes …

Intermediate filaments at the junction of mechanotransduction, migration, and development

R Sanghvi-Shah, GF Weber - Frontiers in cell and developmental …, 2017 - frontiersin.org
Mechanically induced signal transduction has an essential role in development. Cells
actively transduce and respond to mechanical signals and their internal architecture must …

The nucleoskeleton as a genome-associated dynamic'network of networks'

DN Simon, KL Wilson - Nature reviews Molecular cell biology, 2011 - nature.com
In the cytosol, actin polymers, intermediate filaments and microtubules can anchor to cell
surface adhesions and interlink to form intricate networks. This cytoskeleton is anchored to …

Molecular structure of soluble vimentin tetramers

PJ Vermeire, AV Lilina, HM Hashim, L Dlabolová… - Scientific Reports, 2023 - nature.com
Intermediate filaments (IFs) are essential constituents of the metazoan cytoskeleton. A vast
family of cytoplasmic IF proteins are capable of self-assembly from soluble tetrameric …

Structural basis for lamin assembly at the molecular level

J Ahn, I Jo, S Kang, S Hong, S Kim, S Jeong… - Nature …, 2019 - nature.com
Nuclear structure and function are governed by lamins, which are intermediate filaments that
mostly consist of α-helices. Different lamin assembly models have been proposed based on …

Intermediate filament mechanics in vitro and in the cell: from coiled coils to filaments, fibers and networks

S Köster, DA Weitz, RD Goldman, U Aebi… - Current opinion in cell …, 2015 - Elsevier
Intermediate filament proteins form filaments, fibers and networks both in the cytoplasm and
the nucleus of metazoan cells. Their general structural building plan accommodates highly …