T helper type 2 cells (Th2 cells) and group 2 innate lymphoid cells (ILC2s) play an important
role in the pathophysiology of asthma, including airway eosinophilic inflammation. ILC2s are …

abstract Asthma is characterized by increased airway hyperresponsiveness, reversible
airflow limitation, and remodeling due to allergic airway inflammation. Asthma has been …

The recent discovery of new innate lymphoid cells (ILCs) has revolutionized the field of
allergies. Since most allergic diseases induce a type 2 immune response, Th2 cells, which …

Objective Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by a chronic
type 2 inflammatory response in the paranasal sinuses. Group 2 innate lymphoid cells …

A 45-year-old man with allergic bronchopulmonary aspergillosis (ABPA) was treated with
oral prednisolone (PSL)(30 mg/day), inhaled corticosteroids, and long-acting beta2 …

Eosinophilic granulomatosis with polyangiitis (EGPA) refers to systemic vasculitis in patients
with bronchial asthma and eosinophilic rhinosinusitis. Dupilumab has been approved for the …

Background Eosinophilic granulomatosis with polyangiitis (EGPA) is characterized by a
necrotizing vasculitis with tissue and peripheral blood eosinophilia affecting small and …

Asthma is considered a syndrome composed of heterogeneous disorders involving complex
chronic airway inflammation. Patients with severe asthma, prolonged symptoms, and …

Background Group 2 innate lymphoid cells (ILC2s) produce type 2 cytokines by stimulation
with epithelial cell–derived cytokines and are implicated in the pathogenesis of various …

Bronchial asthma is characterized by airway inflammation, airway hyperresponsiveness,
and reversible airway obstruction. Eosinophils contribute to the pathogenesis of airway …