Following its transcription, RNA can be modified by> 170 chemically distinct types of
modifications—the epitranscriptome. In recent years, there have been substantial efforts to …

Gene expression is regulated at many levels including co-or post-transcriptionally, where
chemical modifications are added to RNA on riboses and bases. Expression control via RNA …

Nanopore RNA sequencing shows promise as a method for discriminating and identifying
different RNA modifications in native RNA. Expanding on the ability of nanopore sequencing …

Abstract N6-methyladenosine (m6A) has recently been found abundantly on messenger
RNA and shown to regulate most steps of mRNA metabolism. Several important m6A …

Over 100 types of chemical modifications have been identified in cellular RNAs. While the
5′ cap modification and the poly (A) tail of eukaryotic mRNA play key roles in regulation …

In the past 25 years, genetic and biochemical analyses of ribosome assembly in yeast have
identified most of the factors that participate in this complex pathway and have generated …

5-methylcytosine (m5C) is an abundant RNA modification that's presence is reported in a
wide variety of RNA species, including cytoplasmic and mitochondrial ribosomal RNAs …

ABSTRACT rRNAs are extensively modified during their transcription and subsequent
maturation in the nucleolus, nucleus and cytoplasm. RNA modifications, which are installed …

Abstract N 4-acetylcytidine (ac4C) is an ancient and highly conserved RNA modification that
is present on tRNA and rRNA and has recently been investigated in eukaryotic mRNA …

During ribosome biogenesis, ribosomal RNAs acquire various chemical modifications that
ensure the fidelity of translation, and dysregulation of the modification processes can cause …