Engineering approaches for cardiac organoid formation and their characterization

B Joddar, SL Natividad-Diaz, AE Padilla… - Translational …, 2022 - Elsevier
Cardiac organoids are 3-dimensional (3D) structures composed of tissue or niche-specific
cells, obtained from diverse sources, encapsulated in either a naturally derived or synthetic …

Vascularizing the brain in vitro

A Aazmi, H Zhou, W Lv, M Yu, X Xu, H Yang, YS Zhang… - Iscience, 2022 - cell.com
The brain is arguably the most fascinating and complex organ in the human body.
Recreating the brain in vitro is an ambition restricted by our limited understanding of its …

Evaluation of the morphological and biological functions of vascularized microphysiological systems with supervised machine learning

JJ Tronolone, T Mathur, CP Chaftari, A Jain - Annals of Biomedical …, 2023 - Springer
Vascularized microphysiological systems and organoids are contemporary preclinical
experimental platforms representing human tissue or organ function in health and disease …

Diabetes diminishes muscle precursor cell-mediated microvascular angiogenesis

FM Acosta, S Pacelli, CR Rathbone - Plos one, 2023 - journals.plos.org
The skeletal muscles of Type II diabetic (T2D) patients can be characterized by a reduced
vessel density, corresponding to deficiencies in microvascular angiogenesis. Interestingly …

Digital labeling for 3D histology: segmenting blood vessels without a vascular contrast agent using deep learning

M Lapierre-Landry, Y Liu, M Bayat… - Biomedical Optics …, 2023 - opg.optica.org
Recent advances in optical tissue clearing and three-dimensional (3D) fluorescence
microscopy have enabled high resolution in situ imaging of intact tissues. Using simply …

ML-driven segmentation of microvascular features during histological examination of tissue-engineered vascular grafts

VV Danilov, VV Laptev, KY Klyshnikov… - … in Bioengineering and …, 2024 - frontiersin.org
Introduction The development of next-generation tissue-engineered medical devices such
as tissue-engineered vascular grafts (TEVGs) is a leading trend in translational medicine …

Code-Free Machine Learning Solutions for Microscopy Image Processing: Deep Learning

E Chechekhina, N Voloshin, K Kulebyakin… - … Engineering Part A, 2024 - liebertpub.com
In recent years, there has been a significant expansion in the realm of processing
microscopy images, thanks to the advent of machine learning techniques. These techniques …

Machine Learning Approaches to 3D Models for Drug Screening

VA da Silva, R Sharma, E Shteinberg, V Patel… - Biomedical Materials & …, 2024 - Springer
The creation of precise, functional 3D tissues can enable effective drug screening as well as
advancements in regenerative medicine. However, the inherent limitations present during …

Microfabrication and Characterization of Micro-Stereolithographically 3d Printed, and Double Metallized Bioplates with 3D Microelectrode Arrays for In-Vitro Analysis …

JM Castro, I Johnson… - 2023 IEEE 36th …, 2023 - ieeexplore.ieee.org
This paper reports for the first time a bioplate microfabrication process using 3D printing
technology and a two-step metallization process (ink-casting and sputtering deposition) that …

Перспективы создания искусственных тканей и органов человека на основе метода трехмерной биопечати

ДВ Булгин, АЛ Ковтун, ИВ Решетов… - Вестник …, 2023 - journal.transpl.ru
Аннотация Трехмерная (3D) печать–это процесс послойного создания в пространстве
материального объекта из виртуальной, математической модели. Метод 3D-печати …