[HTML][HTML] Endpoints for clinical trials in ophthalmology

L Schmetterer, H Scholl, G Garhöfer… - Progress in Retinal and …, 2023 - Elsevier
With the identification of novel targets, the number of interventional clinical trials in
ophthalmology has increased. Visual acuity has for a long time been considered the gold …

[HTML][HTML] Early diabetic eye damage: Comparing detection methods using diagnostic power

BB Rai, JP van Kleef, F Sabeti, R Vlieger… - Survey of …, 2024 - Elsevier
It is now clear that retinal neuropathy precedes classical microvascular retinopathy in
diabetes. Therefore, tests that underpin useful new endpoints must provide high diagnostic …

Objective perimetry identifies regional functional progression and recovery in mild Diabetic Macular Oedema

F Sabeti, BB Rai, JP van Kleef, EMF Rohan, CF Carle… - Plos one, 2023 - journals.plos.org
Purpose Retinal function beyond foveal vision is not routinely examined in the clinical
screening and management of diabetic retinopathy although growing evidence suggests it …

Discriminating early-stage diabetic retinopathy with subjective and objective perimetry

F Sabeti, JP van Kleef, RM Iyer, CF Carle… - Frontiers in …, 2024 - frontiersin.org
Introduction To prevent progression of early-stage diabetic retinopathy, we need functional
tests that can distinguish multiple levels of neural damage before classical vasculopathy. To …

[HTML][HTML] Comparing Objective Perimetry, Matrix perimetry, and regional retinal thickness in mild diabetic macular edema

BB Rai, T Maddess, CF Carle… - … vision science & …, 2021 - iovs.arvojournals.org
Purpose: To compare per-region macular sensitivity and delay from objective perimetry with
Matrix perimetry and retinal thickness in mild diabetic macular edema (DMO). Methods …

[HTML][HTML] Rapid objective testing of visual function matched to the ETDRS grid and its diagnostic power in age-related macular degeneration

BB Rai, F Sabeti, CF Carle, EM Rohan… - Ophthalmology …, 2022 - Elsevier
Purpose To study the power of an 80-second multifocal pupillographic objective perimetry
(mfPOP) test tailored to the ETDRS grid to diagnose age-related macular degeneration …

An objective perimetry study of central versus peripheral sensitivities and delays in age-related macular degeneration

BB Rai, RW Essex, F Sabeti, T Maddess… - … Vision Science & …, 2021 - tvst.arvojournals.org
Purpose: The purpose of this study was to compare central versus peripheral retinal
sensitivities and delays in neovascular age-related macular degeneration (nAMD) using US …

Defining the structure–function relationship of specific lesions in early and advanced age-related macular degeneration

TF Tan, CL Yap, CL Peterson, D Wong, TY Wong… - Scientific Reports, 2024 - nature.com
The objective of this study is to define structure–function relationships of pathological lesions
related to age-related macular degeneration (AMD) using microperimetry and multimodal …

[HTML][HTML] Functional diabetic retinopathy: A new concept to improve management of diabetic retinal diseases

BB Rai, T Maddess, CJ Nolan - Survey of Ophthalmology, 2024 - Elsevier
Multifocal functional tests are not routinely performed in diabetic retinopathy (DR) and
diabetic macular edema (DME) management. We emphasise their importance and coin the …

Age-Related Macular or Retinal Degeneration?

M Gałuszka, D Pojda-Wilczek, I Karska-Basta - Medicina, 2023 - mdpi.com
Age-related macular degeneration (AMD) is an eye disease that leads to progressive vision
loss. Its prevalence has been increasing due to population aging. Previously, it was …