The review highlights the hydantoin syntheses presented from the point of view of the
preparation methods. Novel synthetic routes to various hydantoin structures, the advances …

Background: The American trypanosomiasis, Chagas disease, is a parasitic infection
typically spread by triatomine vectors affecting millions of people all over Latin America …

The present study describes synthesizing a novel series of polyfunctionalized pyridine
congeners 1–18 and assessed for cytotoxic efficacies versus HCT-116, MCF-7, and HepG-2 …

A facile and versatile method for generating radicals from Csp3–H bonds under metal-free
and organic-peroxide-free conditions was developed. By combining safe persulfate and low …

Approved drugs for the treatment of Alzheimer's disease belong to the group of inhibitors of
the acetylcholinesterase (AChE) and NMDA receptor inhibitors. However none of the drugs …

Nipah virus (NiV), a highly pathogenic paramyxovirus, causes respiratory disease in pigs
and severe febrile encephalitis in humans with high mortality rates. On the basis of the …

We previously observed that physalins have immunomodulatory properties, as well as
antileishmanial and antiplasmodial activities. Here, we investigated the anti-Trypanosoma …

Hugo Schiff (1834–1915) was born in the vibrant Jewish community in Frankfurt/Main,
Germany. He was a prominent chemist a century ago, and he prepared a new class of …

Chagas disease, a parasitic infection typically spread by triatomine bugs, affects millions of
people throughout Latin America. Current chemotherapy based on the nitroaromatic …

This review intends to summarize the structures of an extensive number of symmetrical-
dimeric drugs, having two monomers, linked via a bridging entity emphasizing the versatility …