Curcumin is a naturally occurring nutraceutical compound with a number of therapeutic and
biological activities such as antioxidant, anti‐inflammatory, anti‐diabetic, antitumor, and …

Antiretroviral therapy controls HIV replication but does not eliminate the virus from the
infected host. The persistence of a small pool of cells harboring integrated and replication …

Long-lasting, latently infected resting CD4+ T cells are the greatest obstacle to obtaining a
cure for HIV infection, as these cells can persist despite decades of treatment with …

Whereas the human fetal immune system is poised to generate immune tolerance and
suppress inflammation in utero, an adult-like immune system emerges to orchestrate anti …

Stem cell-like memory T cells (Tscm), are a newly defined memory T cell subset with
characteristics of long life span, consistent self-renewing, rapid differentiation into effector T …

Much attention has been paid to a newly discovered subset of memory T (TM) cells—stem
cell-like memory T (T SCM) cells for their high self-renewal ability, multi-differentiation …

Latency is the main obstacle towards an HIV cure, with cure strategies aiming to either elicit
or prevent viral reactivation. While these strategies have shown promise, they have only …

ABSTRACT HIV-1 latency posts a major obstacle for HIV-1 eradication. Currently, no
desirable latency reversing agents (LRAs) have been implicated in the “Shock and Kill” …

Rhesus macaques (Macaca mulatta) are among the most extensively studied of nonhuman
primates. This species has been the subject of many investigations concerning basic …

The intestinal environment facilitates HIV-1 infection via mechanisms involving the gut-
homing vitamin A-derived retinoic acid (RA), which transcriptionally reprograms CD4+ T …