Emerging and re-emerging bacterial infections are a serious threat to human and animal
health. Extracellular bacteria are free-living, while facultative intracellular bacteria replicate …

Clinical conditions synonymous with brucellosis have been described since the time of
Hippocrates. Indeed, it has been suggested that organisms resembling brucellae have been …

There is currently no licensed vaccine for brucellosis in humans. Available animal vaccines
may cause disease and are considered unsuitable for use in humans. However, the …

The search for ideal brucellosis vaccines remains active today. Currently, no licensed
human or canine anti-brucellosis vaccines are available. In bovines, the most successful …

Brucella spp. are zoonotic, facultative intracellular pathogens, which cause animal and
human disease. Animal disease results in abortion of fetuses; in humans, it manifests flu-like …

In the present study, a chlorella-free control diet (C) and five experimental diets
supplemented with 0.4~ 2.0% Chlorella were formulated. The gibel carp (Carassius auratus …

Prophylactic vaccines have evolved from traditional whole-cell vaccines to safer subunit
vaccines. However, subunit vaccines still face problems, such as poor immunogenicity and …

The development of an effective subunit vaccine against brucellosis is a research area of
intense interest. The outer membrane proteins (Omps) of Brucella spp. have been …

Brucella spp are intracellular bacteria that cause brucellosis, one of the most common
zoonoses in the world. Given the serious medical consequences of this disease, a safe and …

This study was designed to evaluate the immunogenicity and the protective efficacy of a
divalent fusion DNA vaccine encoding both the Brucella abortus L7/L12 protein (ribosomal …