The extracellular matrix–the under‐recognized element in lung disease?

JK Burgess, T Mauad, G Tjin, JC Karlsson… - The Journal of …, 2016 - Wiley Online Library
The lung is composed of airways and lung parenchyma, and the extracellular matrix (ECM)
contains the main building blocks of both components. The ECM provides physical support …

Dermatan sulfate: new functions from an old glycosaminoglycan

JM Trowbridge, RL Gallo - Glycobiology, 2002 - academic.oup.com
Glycosaminoglycans constitute a considerable fraction of the glycoconjugates found on
cellular membranes and in the extracellular matrix of virtually all mammalian tissues. Their …

Osteogenic differentiation of purified, culture‐expanded human mesenchymal stem cells in vitro

N Jaiswal, SE Haynesworth, AI Caplan… - Journal of cellular …, 1997 - Wiley Online Library
Human bone marrow contains a population of cells capable of differentiating along multiple
mesenchymal cell lineages. Recently, techniques for the purification and culture‐expansion …

Growth kinetics, self‐renewal, and the osteogenic potential of purified human mesenchymal stem cells during extensive subcultivation and following cryopreservation

SP Bruder, N Jaiswal… - Journal of cellular …, 1997 - Wiley Online Library
Recent studies have demonstrated the existence of a subset of cells in human bone marrow
capable of differentiating along multiple mesenchymal lineages. Not only do these …

Cytokine expression by human marrow‐derived mesenchymal progenitor cells in vitro: Effects of dexamethasone and IL‐1α

SE Haynesworth, MA Baber… - Journal of cellular …, 1996 - Wiley Online Library
We previously reported the purification, culture‐expansion, and osteogenic differentiation
potential of mesenchymal progenitor cells (MPCs) derived from human bone marrow. As a …

Adult human mesenchymal stem cell differentiation to the osteogenic or adipogenic lineage is regulated by mitogen-activated protein kinase

RK Jaiswal, N Jaiswal, SP Bruder, G Mbalaviele… - Journal of Biological …, 2000 - ASBMB
Adult human mesenchymal stem cells are primary, multipotent cells capable of
differentiating to osteocytic, chondrocytic, and adipocytic lineages when stimulated under …

Mesenchymal precursor cells in the blood of normal individuals

NJ Zvaifler, L Marinova-Mutafchieva, G Adams… - Arthritis Research & …, 2000 - Springer
Statement of findings Mesenchymal precursor cells found in the blood (BMPCs) of normal
persons adhere to plastic and glass and proliferate logarithmically in DMEM-20% fetal calf …

The role of proteoglycans in cell adhesion, migration and proliferation

TN Wight, MG Kinsella, EE Qwarnström - Current opinion in cell biology, 1992 - Elsevier
Proteoglycans comprise a part of the extracellular matrix that participates in the molecular
events that regulate cell adhesion, migration and proliferation. Their structural diversity and …

Abundance of two human preadipocyte subtypes with distinct capacities for replication, adipogenesis, and apoptosis varies among fat depots

T Tchkonia, YD Tchoukalova… - American Journal …, 2005 - journals.physiology.org
Fat depots vary in function and size. The preadipocytes that fat cells develop from exhibit
distinct regional characteristics that persist in culture. Human abdominal subcutaneous …

Polysaccharide matrices used in 3D in vitro cell culture systems

D Diekjürgen, DW Grainger - Biomaterials, 2017 - Elsevier
Polysaccharides comprise a diverse class of polymeric materials with a history of proven
biocompatibility and continual use as biomaterials. Recent focus on new matrices …