Collagen fibrillogenesis in the mitral valve: it'sa matter of compliance

RL Goodwin, A Kheradvar, RA Norris, RL Price… - Journal of …, 2021 - mdpi.com
Collagen fibers are essential structural components of mitral valve leaflets, their tension
apparatus (chordae tendineae), and the associated papillary muscles. Excess or lack of …

Post-operative ventricular flow dynamics following atrioventricular valve surgical and device therapies: A review

YN Nguyen, M Ismail, F Kabinejadian, ELW Tay… - Medical engineering & …, 2018 - Elsevier
Intra-ventricular flow dynamics has recently emerged as an important evaluation and
diagnosis tool in different cardiovascular conditions. The formation of vortex pattern during …

Vortex‐ring mixing as a measure of diastolic function of the human heart: phantom validation and initial observations in healthy volunteers and patients with heart …

J Töger, M Kanski, PM Arvidsson… - Journal of Magnetic …, 2016 - Wiley Online Library
Purpose To present and validate a new method for 4D flow quantification of vortex‐ring
mixing during early, rapid filling of the left ventricle (LV) as a potential index of diastolic …

Intraventricular vortex interaction between transmitral flow and paravalvular leak

D Morisawa, A Falahatpisheh, E Avenatti, SH Little… - Scientific reports, 2018 - nature.com
Paravalvular leak (PVL) is a complication of transcatheter aortic valve replacement. Despite
its marked clinical impact, no previous study has reported how PVL affects the …

A D-shaped bileaflet bioprosthesis which replicates physiological left ventricular flow patterns

SGD Tan, S Kim, JKF Hon, HL Leo - PloS one, 2016 - journals.plos.org
Prior studies have shown that in a healthy heart, there exist a large asymmetric vortex
structure that aids in establishing a steady flow field in the left ventricle. However, the …

In vivo image-based 4d modeling of competent and regurgitant mitral valve dynamics

AH Aly, AH Aly, EK Lai, N Yushkevich… - Experimental …, 2021 - Springer
Background In vivo characterization of mitral valve dynamics relies on image analysis
algorithms that accurately reconstruct valve morphology and motion from clinical images …

[HTML][HTML] Incorporating the anterior mitral leaflet to the annulus impairs left ventricular function in an ovine model

L Brunel, ZA Williams, M Yata, BM Robinson, IK Wise… - JTCVS open, 2021 - Elsevier
Objectives Transcatheter mitral valve prostheses are designed to capture the anterior leaflet
and surgical techniques designed to fully preserve the subvalvular apparatus at prosthetic …

Naturally designed mitral prosthesis

T Kofidis - US Patent 10,709,560, 2020 - Google Patents
A prosthetic mitral valve designed to resemble a patient's nat-ural mitral valve is provided.
The prosthetic mitral valve includes an asym-metrical, flexible ring dimensioned to match a …

Modeling and numerical simulation of implantable cardiovascular devices

L Boilevin-Kayl - 2019 - inria.hal.science
This thesis, taking place in the context of the Mivana project, is devoted to the modeling and
to the numerical simulation of implantable cardiovascular devices. This project is led by the …

Splitting the anterior mitral leaflet impairs left ventricular function in an ovine model

L Brunel, ZA Williams, K Yastrebov… - European Journal of …, 2023 - academic.oup.com
OBJECTIVES During mitral valve replacement, the anterior mitral leaflet is usually resected
or modified. Anterior leaflet splitting seems the least disruptive modification. Reattachment of …