Drug targeting to tumors: principles, pitfalls and (pre-) clinical progress

T Lammers, F Kiessling, WE Hennink… - Journal of controlled …, 2012 - Elsevier
Many different systems and strategies have been evaluated for drug targeting to tumors over
the years. Routinely used systems include liposomes, polymers, micelles, nanoparticles and …

Threatening cancer with nanoparticle aided combination oncotherapy

S Rawal, MM Patel - Journal of controlled release, 2019 - Elsevier
Employing combination therapy has become obligatory in cancer cases exhibiting high
tumor load, chemoresistant tumor population, and advanced disease stages. Realization of …

RGD-modified apoferritin nanoparticles for efficient drug delivery to tumors

Z Zhen, W Tang, H Chen, X Lin, T Todd, G Wang… - ACS …, 2013 - ACS Publications
Ferritin (FRT) is a major iron storage protein found in humans and most living organisms.
Each ferritin is composed of 24 subunits, which self-assemble to form a cage-like …

Artificial lipid membranes: Past, present, and future

CG Siontorou, GP Nikoleli, DP Nikolelis, SK Karapetis - Membranes, 2017 - mdpi.com
The multifaceted role of biological membranes prompted early the development of artificial
lipid-based models with a primary view of reconstituting the natural functions in vitro so as to …

Active methods of drug loading into liposomes: recent strategies for stable drug entrapment and increased in vivo activity

J Gubernator - Expert opinion on drug delivery, 2011 - Taylor & Francis
Introduction: The use of liposomes increases the therapeutic index of many drugs, and also
offers drug targeting and controlled release. The commercial impact of liposomes is …

Drug delivery by soft matter: matrix and vesicular carriers

E Soussan, S Cassel, M Blanzat… - Angewandte Chemie …, 2009 - Wiley Online Library
The increasing need for drug delivery systems that improve specificity and activity and at the
same time reduce toxicity to ensure maximum treatment safety has led to the development of …

[HTML][HTML] Nanoencapsulation for drug delivery

A Kumari, R Singla, A Guliani, SK Yadav - EXCLI journal, 2014 - ncbi.nlm.nih.gov
Nanoencapsulation of drug/small molecules in nanocarriers (NCs) is a very promising
approach for development of nanomedicine. Modern drug encapsulation methods allow …

Liposomal nanomedicines

DB Fenske, PR Cullis - Expert opinion on drug delivery, 2008 - Taylor & Francis
Liposomal nanoparticles (LNs) encapsulating therapeutic agents, or liposomal
nanomedicines, represent an advanced class of drug delivery systems, with several …

Pharmacokinetics and in vivo drug release rates in liposomal nanocarrier development

DC Drummond, CO Noble, ME Hayes, JW Park… - Journal of …, 2008 - Elsevier
Liposomes represent a widely varied and malleable class of drug carriers generally
characterized by the presence of one or more amphiphile bilayers enclosing an interior …

Liposomes and virosomes as delivery systems for antigens, nucleic acids and drugs

D Felnerova, JF Viret, R Glück, C Moser - Current opinion in biotechnology, 2004 - Elsevier
Lipid-based vesicles are a very promising approach to treat diseases such as cancer,
chronic infections and auto-immunity. Modern drug encapsulation methods allow efficient …