Cartilage defects are one of the most common symptoms of osteoarthritis (OA), a
degenerative disease that affects millions of people world-wide and places a significant …

Recently, understanding of the extracellular matrix (ECM) has expanded rapidly due to the
accessibility of cellular and molecular techniques and the growing potential and value for …

New trends in biomedical applications of the hybrid polymeric hydrogels, obtained by
combining natural polymers with synthetic ones, have been reviewed …

Designing of biologically active scaffolds with optimal characteristics is one of the key factors
for successful tissue engineering. Recently, hydrogels have received a considerable interest …

Hydrogels, due to their unique biocompatibility, flexible methods of synthesis, range of
constituents, and desirable physical characteristics, have been the material of choice for …

Polyethylene glycol (PEG) hydrogels are widely used in a variety of biomedical applications,
including matrices for controlled release of biomolecules and scaffolds for regenerative …

The repair of articular cartilage defects remains a significant challenge in orthopedic
medicine. Hydrogels, three-dimensional polymer networks swollen in water, offer a unique …

With the rapid progress of biomedical technology, hydrogels that can be prepared under bio-
friendly conditions are urgently needed. In situ gelling systems have been extensively …

Replacement of body parts has been studied for at least 2500 years, when missing teeth
were substituted with artificial teeth engraved from the bones of oxen. 1 Artificial substitutes …

Cartilage tissue engineering is emerging as a technique for the regeneration of cartilage
tissue damaged due to disease or trauma. Since cartilage lacks regenerative capabilities, it …