Acute conversion of patient-derived Duchenne muscular dystrophy iPSC into myotubes reveals constitutive and inducible over-activation of TGFβ-dependent pro …

L Caputo, A Granados, J Lenzi, A Rosa, S Ait-Si-Ali… - Skeletal muscle, 2020 - Springer
Abstract Background In Duchenne muscular dystrophy (DMD), DYSTROPHIN deficiency
exposes myofibers to repeated cycles of contraction/degeneration, ultimately leading to …

Gene expression profiling of skeletal myogenesis in human embryonic stem cells reveals a potential cascade of transcription factors regulating stages of myogenesis …

M Shelton, M Ritso, J Liu, D O'Neil, A Kocharyan… - PLoS …, 2019 - journals.plos.org
Human embryonic stem cell (hESC)-derived skeletal muscle progenitors (SMP)—defined as
PAX7-expressing cells with myogenic potential—can provide an abundant source of donor …

[PDF][PDF] Induced pluripotent stem cells and genome editing technology as therapeutic strategies for Duchenne muscular dystrophy

IS Batubara - Journal of the Medical Sciences (Berkala Ilmu …, 2021 - researchgate.net
Duchenne muscular dystrophy (DMD) is a rare genetic, progressive and devastating skeletal
and cardiac muscle disorder due to mutation of the dystrophin gene that affects 1 in 3500 …