Once damaged, articular cartilage has a limited potential to repair. Clinically, a repair tissue
is formed, yet, it is often mechanically inferior fibrocartilage. The use of monolayer expanded …

Biomaterial-based scaffolds are important cues in tissue engineering (TE) applications.
Recent advances in TE have led to the development of suitable scaffold architecture for …

The hyaline cartilage is the most abundant type of cartilage in the body. It is responsible for
the bone formation in the embryo (endochondral ossification) and in adults, it can be found …

Cartilage regeneration and repair remain a clinical challenge due to the limited capability of
cartilage to self-regenerate. Worldwide, the costs associated with cartilage regeneration per …

One of the most important issues facing cartilage tissue engineering is the inability to move
technologies into the clinic. Despite the multitude of current research in the field, it is known …

Painful degeneration of soft tissues accounts for high socioeconomic costs. Tissue
engineering aims to provide biomimetics recapitulating native tissues. Biocompatible …

Chondrogenesis is a highly coordinated event in embryo development, adult homeostasis,
and repair of the vertebrate cartilage. Fate decisions and differentiation of chondrocytes …

This review article focuses on thermoresponsive hydrogels consisting of poloxamers which
are of high interest for biomedical application especially in drug delivery for ophthalmic …

Background Articular cartilage injuries have poor repair capacity, leading to progressive
joint damage, and cannot be restored predictably by either conventional treatments or …

Hydrogels consisting of a three-dimensional hydrophilic network of biocompatible polymers
have been widely used in tissue engineering. Owing to their tunable mechanical properties …