Adequate supply of blood and structural and functional integrity of blood vessels are key to
normal brain functioning. On the other hand, cerebral blood flow shortfalls and blood–brain …

The blood–brain barrier (BBB) is a continuous endothelial membrane within brain
microvessels that has sealed cell-to-cell contacts and is sheathed by mural vascular cells …

Increasing evidence recognizes Alzheimer's disease (AD) as a multifactorial and
heterogeneous disease with multiple contributors to its pathophysiology, including vascular …

The glucose transporter GLUT1 at the blood-brain barrier (BBB) mediates glucose transport
into the brain. Alzheimer's disease is characterized by early reductions in glucose transport …

Rationale: Recent evidence suggests that obstructive sleep apnea (OSA) may be a risk
factor for developing mild cognitive impairment and Alzheimer's disease. However, how …

Objective To examine in a 3-year brain imaging study the effects of higher vs lower
adherence to a Mediterranean-style diet (MeDi) on Alzheimer disease (AD) biomarker …

The accumulation of amyloid-β (Aβ) plaques is a central feature of Alzheimer's disease (AD).
First reported in animal models, it remains uncertain if peripheral inflammatory and/or …

Alzheimer's disease (AD) is an age-dependent neurodegenerative disorder associated with
progressive loss of cognitive function. 2-[18 F] fluoro-2-deoxy-d-glucose (FDG) positron …

Use of biomarkers in the detection of early and preclinical Alzheimer's disease (AD) has
become of central importance following publication of the NIA-Alzheimer's Association …

To determine the relationship between amyloid burden and neural function in healthy adults
at risk for Alzheimer's Disease (AD), we used multimodal imaging with [C-11] Pittsburgh …