One of the grand challenges of biophysical chemistry is to understand the principles that
govern protein misfolding and aggregation, which is a highly complex process that is …

Fluorescence correlation spectroscopy (FCS) is a widely used technique in biophysics and
has helped address many questions in the life sciences. It provides important advantages …

Single-plane illumination (SPIM) or total internal reflection fluorescence (TIRF) microscopes
can be combined with fast and single-molecule-sensitive cameras to allow spatially resolved …

The plasma membrane is a complex fluid where lipids and proteins undergo diffusive motion
critical to biochemical reactions. Through quantitative imaging analyses such as single …

The human islet amyloid polypeptide (hIAPP) or amylin, a neuroendocrine peptide hormone,
is known to misfold and form amyloidogenic aggregates that have been observed in the …

Amyloid formation continues to be a widely studied area due to its association with
numerous diseases, such as Alzheimer's and Parkinson's diseases. Despite a large body of …

The spatial arrangement of the epidermal growth factor receptor (EGFR) on the cellular
plasma membrane is one of the prime factors that control its downstream signaling pathways …

Nanomaterials are utilized in a wide array of end user products such as pharmaceuticals,
electronics, clothes and cosmetic products. Due to its size (< 100 nm), nanoparticles have …

Fluorescence fluctuation spectroscopy (FFS) techniques provide information at the single-
molecule level with excellent time resolution. Usually applied at a single spot in a sample …

Interaction of human islet amyloid polypeptide (hIAPP) peptides with cell membrane is
crucial for the understanding of amyloid toxicity associated with Type II diabetes (T2D) …