Synergistic effect of carnosine on browning of adipose tissue in exercised obese rats; a focus on circulating irisin levels

MF Schaalan, BK Ramadan… - Journal of cellular …, 2018 - Wiley Online Library
The recent appreciation of the energy burning capacity of brown adipose tissue turns it to an
attractive target for anti‐obesity therapy. We sought to evaluate the effect of L‐carnosine on …

Hyperlipidemia and male infertility

ZB Hamad Zubi, HA Hamad Alfarisi - Egyptian Journal of Basic and …, 2021 - Taylor & Francis
Hyperlipidemia is a common disease affecting 25% of adults in developed nations.
Approximately 50% of the middle-aged adult population have been reported to have total …

[HTML][HTML] Phenolic compounds and the anti-atherogenic effect of bee bread in high-fat diet-induced obese rats

ZA Othman, WS Wan Ghazali, L Noordin… - Antioxidants, 2019 - mdpi.com
This study was undertaken to determine the phenolic compounds and the anti-atherogenic
effect of bee bread in high-fat diet (HFD)-induced obese rats. The presence of phenolic …

Obesity-induced testicular oxidative stress, inflammation and apoptosis: Protective and therapeutic effects of orlistat

JB Suleiman, VU Nna, Z Zakaria, ZA Othman… - Reproductive …, 2020 - Elsevier
Obesity has been reported to induce oxidative stress, inflammation and apoptosis in the
testis. The objective of this study was to determine the effects of the anti-obesity drug orlistat …

[HTML][HTML] Male reproductive traits are differentially affected by dietary macronutrient balance but unrelated to adiposity

AJ Crean, S Afrin, H Niranjan, TJ Pulpitel… - Nature …, 2023 - nature.com
Dietary factors influence male reproductive function in both experimental and
epidemiological studies. However, there are currently no specific dietary guidelines for male …

A mechanistic exploration of the metabolome of African mango seeds and its potential to alleviate cognitive impairment induced by high-fat/high-carbohydrate diets …

YR Hassan, RA El-Shiekh, HM El Hefnawy… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Irvingia gabonensis (Aubry-Lecomte ex O'Rorke)
Baill., also known as “African mango” or “bush mango”, belonging to family Irvingiaceae, has …

Orlistat attenuates obesity‐induced decline in steroidogenesis and spermatogenesis by up‐regulating steroidogenic genes

JB Suleiman, VU Nna, ZA Othman, Z Zakaria… - …, 2020 - Wiley Online Library
Background Steroidogenesis decline is reported to be one of the mechanisms associated
with obesity‐induced male factor subfertility/infertility. Objectives We explored the possible …

Intermittent fasting attenuates high-fat diet-induced cerebellar changes in rats: involvement of tnf-α, autophagy, and oxidative stress

HA Ebrahim, R El-Gamal, RN Sherif - Cells Tissues Organs, 2021 - karger.com
Obesity has become a prevalent global health issue, and recently it has been reported to be
intimately associated with neuronal health. Obesity triggers peripheral inflammatory …

[HTML][HTML] Orlistat mitigates oxidative stress-linked myocardial damage via NF-κβ-and caspase-dependent activities in obese rats

ZA Othman, Z Zakaria, JB Suleiman… - International Journal of …, 2022 - mdpi.com
Oxidative stress contributes to major complications of obesity. This study intended to identify
whether orlistat could mitigate myocardial damage in obese animal models. The tested rats …

Antiobesity Activities of Methanolic Extracts of Amaranthus dubius, Cucurbita pepo, and Vigna unguiculata in Progesterone‐Induced Obese Mice

KW Nderitu, NS Mwenda, NJ Macharia… - Evidence‐Based …, 2017 - Wiley Online Library
Amaranthus dubius, Vigna unguiculata, and Cucurbita pepo are traditionally used to
manage obesity in Kenya but lack scientific validation to support their use. The aim of this …