Catalytic hairpin assembly as cascade nucleic acid circuits for fluorescent biosensor: Design, evolution and application

Z Luo, Y Li, P Zhang, L He, Y Feng, Y Feng… - TrAC Trends in …, 2022 - Elsevier
Catalytic hairpin assembly (CHA) with advantages of high efficiency, flexible design, and
mild reaction condition is considered a promising molecular amplifier. Modified working …

[HTML][HTML] SERS sensing for cancer biomarker: Approaches and directions

L Vázquez-Iglesias, GMS Casagrande, D García-Lojo… - Bioactive Materials, 2024 - Elsevier
These days, cancer is thought to be more than just one illness, with several complex
subtypes that require different screening approaches. These subtypes can be distinguished …

Aptamer-based point-of-care devices: Emerging technologies and integration of computational methods

Y Aslan, M Atabay, HK Chowdhury, I Göktürk, Y Saylan… - Biosensors, 2023 - mdpi.com
Recent innovations in point-of-care (POC) diagnostic technologies have paved a critical
road for the improved application of biomedicine through the deployment of accurate and …

Kill three birds with one stone: Zr-MOF-mediated composite multi-functional materials to enhance the efficiency for fluorescent and colorimetric dual-signal readout …

F Hong, L Ren, Y Chen - Chemical Engineering Journal, 2023 - Elsevier
In this work, we report a fluorescent and colorimetric dual readout bioassay for
deoxynivalenol detection to ensure public food safety. A multifunctional fluorescent and …

Homogeneous binary visual and fluorescence detection of tetanus toxoid in clinical samples based on enzyme-free parallel hybrid chain reaction

P Chen, Y Bai, S Tang, N Wang, Y He, K Huang… - Nano Letters, 2022 - ACS Publications
Here, we report a simple aptamer-based toxoid test with both fluorescence and binary visual
readouts. This test is established based on our recent finding that CdTe quantum dots could …

Translation of aptamers toward clinical diagnosis and commercialization

S Liu, Y Xu, X Jiang, H Tan, B Ying - Biosensors and Bioelectronics, 2022 - Elsevier
The dominance of antibodies in diagnostics has gradually changed following the discovery
of aptamers in the early 1990s. Aptamers offer inherent advantages over traditional …

Nanoarchitectonics-assisted simultaneous fluorescence detection of urinary dual miRNAs for noninvasive diagnosis of prostate cancer

P Jiang, Y Bai, L Yan, P Feng, K Huang… - Analytical …, 2023 - ACS Publications
Herein, we report a fluorescence strategy for the homogeneous and simultaneous analysis
of urine miRNA-375 and miRNA-148a. The target miRNAs in urine bonded the devised …

Magnetic capture of sulfur quantum dots encapsulated in MOF-5-NH2 via a target-driven self-cycling catalyzed hairpin assembly for the sensitive detection of patulin

X Yan, Y Zhao, G Du, Q Guo, H Chen, Q He… - Chemical Engineering …, 2022 - Elsevier
Tools to detect low molecular weight mycotoxin patulin (PAT) are urgently needed because
of its harm to human health. Here, we report a simple, effective, and sensitive fluorescent …

“Three-in-one” Zr-MOF multifunctional carrier-mediated fluorescent and colorimetric dual-signal readout biosensing platform to enhance analytical performance

L Ren, F Hong, L Zeng, Y Chen - ACS Applied Materials & …, 2022 - ACS Publications
To address the urgent demand for sensitive and stable detection applications, significant
efforts have been made in the development of dual-signal readout assays for precise target …

Simplified rapid enrichment of CTCs and selective recognition prereduction enable a homogeneous ICP-MS liquid biopsy strategy of lung cancer

Y Wang, X Chen, X Shen, Y He, Z Zhan, C Liu… - Analytical …, 2023 - ACS Publications
The effective enrichment and hypersensitivity analysis of circulating tumor cells (CTCs) in
clinical whole blood samples are highly significant for clinical tumor liquid biopsy. In this …