[HTML][HTML] MicroRNAs as biomarkers in solid organ transplantation

VR Mas, CI Dumur, MJ Scian, RC Gehrau… - American Journal of …, 2013 - Elsevier
Important progress has been made in improving short-term outcomes in solid organ
transplantation. However, long-term outcomes have not improved during the last decades …

Solid phase HLA antibody detection technology–challenges in interpretation

BD Tait, F Hudson, G Brewin, L Cantwell… - Tissue …, 2010 - Wiley Online Library
The introduction into routine diagnostic laboratories of solid phase assays for human
leukocyte antigen (HLA) antibody detection has resulted in the application of new laboratory …

[HTML][HTML] The urine microRNA profile may help monitor post-transplant renal graft function

DG Maluf, CI Dumur, JL Suh, MJ Scian, AL King… - Kidney international, 2014 - Elsevier
Noninvasive, cost-effective biomarkers that allow accurate monitoring of graft function are
needed in kidney transplantation. Since microRNAs (miRNAs) have emerged as promising …

Application of ultrasound-targeted microbubble destruction–mediated exogenous gene transfer in treating various renal diseases

S Huang, Y Ren, X Wang, L Lazar, S Ma… - Human gene …, 2019 - liebertpub.com
Chronic renal disease or acute renal injury could result in end-stage renal disease or renal
failure. Sonoporation, induced by ultrasound-targeted microbubble destruction (UTMD), has …

Hepatocyte viability and adenosine triphosphate content decrease linearly over time during conventional cold storage of rat liver grafts

TA Berendsen, ML Izamis, H Xu, Q Liu, M Hertl… - Transplantation …, 2011 - Elsevier
Introduction The gold standard in organ preservation is static cold storage (SCS) using
University of Wisconsin solution (UW). Although it is well-known that there is a finite limit to …

Computational pathology model to assess acute and chronic transformations of the tubulointerstitial compartment in renal allograft biopsies

R Augulis, A Rasmusson, A Laurinaviciene, KY Jen… - Scientific Reports, 2024 - nature.com
Managing patients with kidney allografts largely depends on biopsy diagnosis which is
based on semiquantitative assessments of rejection features and extent of acute and chronic …

Increased macrophage density of cardiac allograft biopsies is associated with antibody‐mediated rejection and alloantibodies to HLA antigens

L Xu, J Collins, C Drachenberg… - Clinical …, 2014 - Wiley Online Library
Background Antibody‐mediated rejection (AMR) is characterized histologically by
intracapillary macrophages. Macrophage density may be an alternative method of …

[HTML][HTML] Mechanisms and risk assessment of steroid resistance in acute kidney transplant rejection

NV Rekers, JW De Fijter, FHJ Claas, M Eikmans - Transplant immunology, 2016 - Elsevier
Ever since the first successful kidney transplantation, the occurrence of acute rejection has
been a dominant risk factor for adverse graft outcome, as it is associated with reduced graft …

Expression and regulation profile of mature microRNA in the pig: Relevance to xenotransplantation

Z Song, DKC Cooper, Z Cai… - BioMed Research …, 2018 - Wiley Online Library
The pig is an important source of meat production and provides a valuable model for certain
human diseases. MicroRNA (miRNA), which is noncoding RNA and regulates gene …

Antibody‐mediated rejection (AMR) after pancreas and pancreas–kidney transplantation

ÉB Rangel, DMAC Malheiros… - Transplant …, 2010 - Wiley Online Library
Antibody‐mediated rejection (AMR) requires specific diagnostic tools and treatment and is
associated with lower graft survival. We prospectively screened C4d in pancreas (n= 35, in …