Marine natural products

JW Blunt, BR Copp, RA Keyzers, MHG Munro… - Natural product …, 2017 - pubs.rsc.org
Covering: 2015. Previous review: Nat. Prod. Rep., 2016, 33, 382–431 This review covers the
literature published in 2015 for marine natural products (MNPs), with 1220 citations (792 for …

Pitfalls in the structural elucidation of small molecules. A critical analysis of a decade of structural misassignments of marine natural products

SM Shen, G Appendino, YW Guo - Natural Product Reports, 2022 - pubs.rsc.org
Covering: July 2010 to August 2021 This article summarizes more than 200 cases of
misassigned marine natural products reported between July 2010 and August 2021, sorting …

[PDF][PDF] Natural product reports

JW Blunt, BR Copp, RA Keyzers, MH Munroa… - Nat Prod Rep, 2016 - academia.edu
This review covers the literature published in 2015 for marine natural products (MNPs), with
1220 citations (792 for the period January to December 2015) referring to compounds …

ortho-Quinone methides as key intermediates in cascade heterocyclizations

DV Osipov, VA Osyanin… - Russian Chemical …, 2017 - iopscience.iop.org
Abstract Development of new methods of heterocyclic synthesis is still a topical issue. In this
connection, the trend related to the use of highly reactive o-quinone methides for the …

Biomimetic dearomatization strategies in the total synthesis of meroterpenoid natural products

JH George - Accounts of Chemical Research, 2021 - ACS Publications
Conspectus Natural products are biosynthesized from a limited pool of starting materials via
pathways that obey the same chemical logic as textbook organic reactions. Given the …

Stereoselective reactions of ortho-quinone methide and ortho-quinone methide imines and their utility in natural product synthesis

CDT Nielsen, H Abas, AC Spivey - Synthesis, 2018 - thieme-connect.com
Herein presented is a review of the reactivity and synthetic utility of ortho-quinone methides
and ortho-quinone methide imines. These versatile intermediates have received significant …

A systematic review of recently reported marine derived natural product kinase inhibitors

T Li, N Wang, T Zhang, B Zhang, TP Sajeevan… - Marine drugs, 2019 - mdpi.com
Protein kinases are validated drug targets for a number of therapeutic areas, as kinase
deregulation is known to play an essential role in many disease states. Many investigated …

Late-stage terpene cyclization by an integral membrane cyclase in the biosynthesis of isoprenoid epoxycyclohexenone natural products

MC Tang, X Cui, X He, Z Ding, T Zhu, Y Tang… - Organic letters, 2017 - ACS Publications
Macrophorins are representative examples of isoprenoid epoxycyclohexenones containing
cyclized drimane moieties. We located and characterized the biosynthetic gene cluster of …

Biomimetic total synthesis of hyperjapones A–E and hyperjaponols A and C

HC Lam, JTJ Spence, JH George - Angewandte Chemie, 2016 - Wiley Online Library
Hyperjapones A–E and hyperjaponols A–C are complex natural products of mixed aromatic
polyketide and terpene biosynthetic origin that have recently been isolated from Hypericum …

Alternarin A, a Drimane Meroterpenoid, Suppresses Neuronal Excitability from the Coral-Associated Fungi Alternaria sp. ZH-15

HL Wang, R Li, J Li, J He, ZY Cao, T Kurtán… - Organic …, 2020 - ACS Publications
Alternarin A (1), a rearranged drimane meroterpenoid characterized by a thioglycerate
moiety, was isolated together with two known analogues from the coral-associated fungi …