Talaromycosis is an invasive mycosis endemic in tropical and subtropical Asia and is
caused by the pathogenic fungus Talaromyces marneffei. Approximately 17,300 cases of T …

Candida tropicalis has emerged as one of the most important Candida species. It has been
widely considered the second most virulent Candida species, only preceded by C. albicans …

Calcium is an abundant intracellular ion, and calcium homeostasis plays crucial roles in
several cellular processes. The calcineurin signaling cascade is one of the major pathways …

The morbidity and mortality caused by invasive fungal infections are increasing across the
globe due to developments in transplant surgery, the use of immunosuppressive agents …

In recent years, the relevance of diseases associated with fungal pathogens increased
worldwide. Members of the Candida genus are responsible for the greatest number of fungal …

Candidiasis has increased significantly recently that threatens patients with low immunity.
However, the number of antifungal drugs on the market is limited in comparison to the …

Antifungal resistance in humans, animals, and the environment is an emerging problem.
Among the different fungal species that can develop resistance, Candida tropicalis is …

Only four species, Candida albicans, C. glabrata, C. parapsilosis, and C. tropicalis, together
account for about 90% of all Candida bloodstream infections and are among the most …

Echinocandins show fungicidal activity against common invasive mycoses but are ineffective
against cryptococcosis. The underlying mechanism for echinocandin resistance in …

Aneuploidy is common both in tumor cells responding to chemotherapeutic agents and in
fungal cells adapting to antifungal drugs. Because aneuploidy simultaneously affects many …