Neurotoxic effects of organophosphorus pesticides and possible association with neurodegenerative diseases in man: A review

M Jokanović - Toxicology, 2018 - Elsevier
In this article the neurotoxic disorders appearing in patients exposed to organophosphorus
pesticides and known mechanisms involved are reviewed. Organophosphorus compounds …

Multiple neurological effects associated with exposure to organophosphorus pesticides in man

M Jokanović, P Oleksak, K Kuca - Toxicology, 2023 - Elsevier
This article reviews available data regarding the possible association of organophosphorus
(OP) pesticides with neurological disorders such as dementia, attention deficit hyperactivity …

Organophosphorus compounds as chemical warfare agents: a review

RT Delfino, TS Ribeiro… - Journal of the Brazilian …, 2009 - SciELO Brasil
Chemical warfare agents constitute one of the greatest threats in the modern world. Among
them, the neurotoxic agents are of special interest due to their high lethality and danger …

Oximes in organophosphate poisoning: 60 years of hope and despair

F Worek, H Thiermann, T Wille - Chemico-biological interactions, 2016 - Elsevier
The high number of annual fatalities following suicidal poisoning by organophosphorus (OP)
pesticides and the recent homicidal use of the chemical warfare nerve agent sarin against …

Medical treatment of acute poisoning with organophosphorus and carbamate pesticides

M Jokanović - Toxicology letters, 2009 - Elsevier
Organophosphorus compounds (OPs) are used as pesticides and developed as warfare
nerve agents such as tabun, soman, sarin, VX and others. Exposure to even small amounts …

Acetylcholinesterase inhibitors (nerve agents) as weapons of mass destruction: History, mechanisms of action, and medical countermeasures

V Aroniadou-Anderjaska, JP Apland, TH Figueiredo… - …, 2020 - Elsevier
Nerve agents are organophosphorus acetylcholinesterase inhibitors. Acute exposure to
nerve agents can cause rapid death. In this review, we summarize the history of nerve agent …

[HTML][HTML] Intoxicación por organofosforados

DG Fernández, LC Mancipe, DC Fernández - Revista Med, 2010 - scielo.org.co
Los compuestos organofosforados son un grupo de sustancias orgánicas derivadas de la
estructura química del fósforo y tienen un gran número de aplicaciones y utilidades. Han …

Resurrection and reactivation of acetylcholinesterase and butyrylcholinesterase

AJ Franjesevic, SB Sillart, JM Beck… - … A European Journal, 2019 - Wiley Online Library
Organophosphorus (OP) nerve agents and pesticides present significant threats to civilian
and military populations. OP compounds include the nefarious G and V chemical nerve …

Pyridinium oximes as cholinesterase reactivators. Structure-activity relationship and efficacy in the treatment of poisoning with organophosphorus compounds

M Jokanovic, M Prostran - Current Medicinal Chemistry, 2009 - ingentaconnect.com
During more than five decades, pyridinium oximes have been developed as therapeutic
agents used in the medical treatment of poisoning with organophosphorus compounds …

Neurotoxic effects in patients poisoned with organophosphorus pesticides

M Jokanović, M Kosanović - Environmental toxicology and pharmacology, 2010 - Elsevier
In this paper we review neurotoxic disorders appearing in patients poisoned with
organophosphorus pesticides. These compounds cause four important neurotoxic effects in …