Thrombotic thrombocytopenic purpura (TTP; also known as Moschcowitz disease) is characterized by the concomitant occurrence of often severe thrombocytopenia …
T Chiasakul, A Cuker - Hematology 2014, the American Society …, 2018 - ashpublications.org
Thrombotic thrombocytopenia purpura (TTP) is a rare, life-threatening disease with an incidence of approximately 2 persons per million per year. It is characterized by severe …
R Raina, V Krishnappa, T Blaha, T Kann… - Therapeutic …, 2019 - Wiley Online Library
Atypical hemolytic uremic syndrome (aHUS), a rare variant of thrombotic microangiopathy, is characterized by microangiopathic hemolytic anemia, thrombocytopenia, and renal …
P Coppo, M Schwarzinger, M Buffet, A Wynckel… - PloS one, 2010 - journals.plos.org
Severe ADAMTS13 deficiency occurs in 13% to 75% of thrombotic microangiopathies (TMA). In this context, the early identification of a severe, antibody-mediated, ADAMTS13 …
M Scully, H Yarranton, R Liesner… - British journal of …, 2008 - Wiley Online Library
Thrombotic thrombocytopenic purpura (TTP) is an acute, rare, life‐threatening disorder. This report presents the South East (SE) England registry for TTP, from April 2002 to December …
M Scully, H Cohen, J Cavenagh… - British journal of …, 2007 - Wiley Online Library
Thrombotic thrombocytopenic purpura (TTP) is a life‐threatening disorder and plasma exchange (PEX) remains the primary treatment modality. Twenty‐five patients with acute …
F Peyvandi, S Lavoretano, R Palla, HB Feys… - …, 2008 - research.unipd.it
BACKGROUND: From 20 to 50% of patients who survive an acute episode of the acquired form of thrombotic thrombocytopenic purpura relapse but clinical and laboratory markers of …
E Roose, AS Schelpe, E Tellier… - Blood, The Journal …, 2020 - ashpublications.org
Recently, we showed that ADAMTS13 circulates in an open conformation during the acute phase of immune-mediated thrombotic thrombocytopenic purpura (iTTP). Although the …
F Alwan, C Vendramin… - Blood, The Journal …, 2017 - ashpublications.org
Immune-mediated thrombotic thrombocytopenic purpura (TTP) is a life-threatening disorder caused by antibodies against ADAMTS13. From the United Kingdom TTP registry, we …