Angiotensin-converting enzyme 2: SARS-CoV-2 receptor and regulator of the renin-angiotensin system: celebrating the 20th anniversary of the discovery of ACE2
ACE2 (angiotensin-converting enzyme 2) has a multiplicity of physiological roles that
revolve around its trivalent function: a negative regulator of the renin-angiotensin system …
revolve around its trivalent function: a negative regulator of the renin-angiotensin system …
[HTML][HTML] Angiotensin-converting enzyme 2—at the heart of the COVID-19 pandemic
ACE2 is the indispensable entry receptor for SARS-CoV and SARS-CoV-2. Because of the
COVID-19 pandemic, it has become one of the most therapeutically targeted human …
COVID-19 pandemic, it has become one of the most therapeutically targeted human …
ACE2 imbalance as a key player for the poor outcomes in COVID-19 patients with age-related comorbidities–role of gut microbiota dysbiosis
Abstract Coronavirus disease 19 (COVID-19) is a pandemic condition caused by the new
coronavirus SARS-CoV-2. The typical symptoms are fever, cough, shortness of breath …
coronavirus SARS-CoV-2. The typical symptoms are fever, cough, shortness of breath …
The gut microbiota–brain axis in neurological disorder
H Ullah, S Arbab, Y Tian, C Liu, Y Chen… - Frontiers in …, 2023 - frontiersin.org
The gut microbiota (GM) plays an important role in the physiology and pathology of the host.
Microbiota communicate with different organs of the organism by synthesizing hormones …
Microbiota communicate with different organs of the organism by synthesizing hormones …
Intestinal barrier dysfunction as a therapeutic target for cardiovascular disease
CV Lewis, WR Taylor - American Journal of Physiology …, 2020 - journals.physiology.org
The gut microbiome and intestinal dysfunction have emerged as potential contributors to the
development of cardiovascular disease (CVD). Alterations in gut microbiome are well …
development of cardiovascular disease (CVD). Alterations in gut microbiome are well …
Fluid and electrolyte disturbances in COVID‐19 and their complications
M Pourfridoni, SM Abbasnia, F Shafaei… - BioMed Research …, 2021 - Wiley Online Library
The novel coronavirus disease 2019 (COVID‐19) is the cause of an acute respiratory illness
which has spread around the world. The virus infects the host by binding to the angiotensin …
which has spread around the world. The virus infects the host by binding to the angiotensin …
Obesity and diabetes as comorbidities for COVID-19: Underlying mechanisms and the role of viral–bacterial interactions
IL Kruglikov, M Shah, PE Scherer - Elife, 2020 - elifesciences.org
Obesity and diabetes are established comorbidities for COVID-19. Adipose tissue
demonstrates high expression of ACE2 which SARS-CoV-2 exploits to enter host cells. This …
demonstrates high expression of ACE2 which SARS-CoV-2 exploits to enter host cells. This …
SARS-CoV-2 infections and ACE2: clinical outcomes linked with increased morbidity and mortality in individuals with diabetes
Individuals with diabetes suffering from coronavirus disease 2019 (COVID-19) exhibit
increased morbidity and mortality compared with individuals without diabetes. In this …
increased morbidity and mortality compared with individuals without diabetes. In this …
The gut–eye axis: lessons learned from murine models
JL Floyd, MB Grant - Ophthalmology and therapy, 2020 - Springer
A healthy gut microbiota is essential in maintaining the human body in a homeostatic state
by its functions in digestion and immune tolerance. Under states of aberrant microbial …
by its functions in digestion and immune tolerance. Under states of aberrant microbial …
ACE2 (Angiotensin-Converting Enzyme 2) in cardiopulmonary diseases: ramifications for the control of SARS-CoV-2
Discovery of ACE2 (angiotensin-converting enzyme 2) revealed that the renin-angiotensin
system has 2 counterbalancing arms. ACE2 is a major player in the protective arm, highly …
system has 2 counterbalancing arms. ACE2 is a major player in the protective arm, highly …