Recalibration of MARTINI-3 Parameters for Improved Interactions between Peripheral Proteins and Lipid Bilayers

J Soni, S Gupta, T Mandal - Journal of Chemical Theory and …, 2024 - ACS Publications
The MARTINI force field is one of the most used coarse-grained models for biomolecular
simulations. Many limitations of the model including the protein–protein overaggregation …

Triazole-Bridged Peptides with Enhanced Antimicrobial Activity and Potency against Pathogenic Bacteria

J Grabeck, J Mayer, A Miltz, M Casoria… - ACS Infectious …, 2024 - ACS Publications
There are still no linear antimicrobial peptides (AMPs) available as a treatment option
against bacterial infections. This is caused by several drawbacks that come with AMPs such …

Screening and computational characterization of novel antimicrobial cathelicidins from amphibian transcriptomic data

H Varela-Rodríguez, A Guzman-Pando… - … Biology and Chemistry, 2024 - Elsevier
As cold-blooded organisms living in damp and dark environments, amphibians have
evolved robust defense mechanisms to protect themselves from predators and infections …

[图书][B] Cardiolipin Modulates the Insertion of Adsorbed Helical Amyloid Beta Peptide Into Model Mitochondrial Membranes

JA Kaczmarek - 2023 - search.proquest.com
The loss of mitochondrial phospholipid cardiolipin (CL) may play a role in both the
pathogenesis of Alzheimer's Disease (AD) and its treatment. An effector molecule of the …