Glial cells are abundant in the CNS and are essential for brain development and
homeostasis. These cells also regulate tissue recovery after injury and their dysfunction is a …

As one of the first defenders of innate immune response, neutrophils make a rapid and
robust response against infection or harmful agents. While traditionally regarded as suicidal …

The regenerative potential of mammalian peripheral nervous system neurons after injury is
critically limited by their slow axonal regenerative rate. Regenerative ability is influenced by …

Transected axons typically fail to regenerate in the central nervous system (CNS), resulting
in chronic neurological disability in individuals with traumatic brain or spinal cord injury …

Spinal cord injury (SCI) lesions present diverse challenges for repair strategies.
Anatomically complete injuries require restoration of neural connectivity across lesions …

Traditionally, neutrophils have been acknowledged to be the first immune cells that are
recruited to an inflamed tissue and have mainly been considered in the context of acute …

Neutrophils are the most abundant immune cells in humans and serve as first responders to
a myriad of host perturbations. Equipped with a plethora of antimicrobial molecules …

Neuroinflammation has positive and negative effects. This review focuses on the roles of
macrophage in the PNS. Transection of PNS axons leads to degeneration and clearance of …

Traumatic optic neuropathy (TON) refers to a pathological condition caused by a direct or
indirect insult to the optic nerves, which often leads to a partial or permanent vision deficit …

Fighting pathogens and maintaining tissue homeostasis are prerequisites for survival. Both
of these functions are upheld by the immune system, though the latter is often overlooked in …