Epizootic of enterocolitis and clostridial overgrowth in NSG and NSG-related mouse strains

JD Arthur, JL Mullen, FA Uzal… - Veterinary …, 2024 - journals.sagepub.com
While the immunodeficient status of NOD. Cg-Prkdc scid Il2rg tm1Wjl/SzJ (NSG) and NSG-
related mice provides utility for numerous research models, it also results in increased …

Outbreaks of Typhlocolitis caused by hypervirulent group ST1 Clostridioides difficile in highly immunocompromised strains of mice

KGL Ma, K Lertpiriyapong, A Piersigilli… - Comparative …, 2020 - ingentaconnect.com
Clostridioides difficile is an enteric pathogen that can cause significant clinical disease in
both humans and animals. However, clinical disease arises most commonly after treatment …

Immunodeficient and humanized mice

SF Santagostino, S Monette, A Piersigilli… - … and Other Mutant …, 2021 - Wiley Online Library
To better study the interaction between tumors and the immune system, scientists have
attempted to create humanized mice in which certain types of hematopoietic cells are …