[HTML][HTML] Changing epidemiology, global trends and implications for outcomes of NAFLD

VWS Wong, M Ekstedt, GLH Wong, H Hagström - Journal of hepatology, 2023 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) has rapidly become the most common liver
disease globally and is currently estimated to affect 38% of the global population. Only a …

Global epidemiology and genetics of hepatocellular carcinoma

MR Toh, EYT Wong, SH Wong, AWT Ng, LH Loo… - Gastroenterology, 2023 - Elsevier
Hepatocellular carcinoma (HCC) is one of the leading cancers worldwide. Classically, HCC
develops in genetically susceptible individuals who are exposed to risk factors, especially in …

Changing epidemiology of hepatocellular carcinoma in Asia

C Zhang, Y Cheng, S Zhang, J Fan, Q Gao - Liver International, 2022 - Wiley Online Library
Liver cancer is the fifth most common cancer and the second leading cause of malignant
death in Asia, and Asia reports 72.5% of the world's cases in 2020. As the most common …

Liver diseases and hepatocellular carcinoma in the Asia-Pacific region: burden, trends, challenges and future directions

LY Mak, K Liu, S Chirapongsathorn, KC Yew… - Nature Reviews …, 2024 - nature.com
Globally, nearly half of deaths from cirrhosis and chronic liver diseases (CLD) and three-
quarters of deaths from hepatocellular carcinoma (HCC) occur in the Asia-Pacific region …

Geographical similarity and differences in the burden and genetic predisposition of NAFLD

TCF Yip, E Vilar‐Gomez, S Petta, Y Yilmaz… - Hepatology, 2023 - journals.lww.com
NAFLD has become a major public health problem for more than 2 decades with a growing
prevalence in parallel with the epidemic of obesity and type 2 diabetes (T2D). The disease …

Biomarkers for diagnosis and therapeutic options in hepatocellular carcinoma

YT Chan, C Zhang, J Wu, P Lu, L Xu, H Yuan, Y Feng… - Molecular Cancer, 2024 - Springer
Liver cancer is a global health challenge, causing a significant social-economic burden.
Hepatocellular carcinoma (HCC) is the predominant type of primary liver cancer, which is …

[HTML][HTML] Asian perspective on NAFLD-associated HCC

TCF Yip, HW Lee, WK Chan, GLH Wong… - Journal of hepatology, 2022 - Elsevier
Recent data suggest that non-alcoholic fatty liver disease (NAFLD) has become a major
public health problem in Asia, with an updated population prevalence of 34%. In parallel …

[HTML][HTML] MAFLD enhances clinical practice for liver disease in the Asia-Pacific region

T Kawaguchi, T Tsutsumi, D Nakano… - Clinical and …, 2022 - ncbi.nlm.nih.gov
Fatty liver is now a major cause of liver disease in the Asia-Pacific region. Liver diseases in
this region have distinctive characteristics. First, fatty liver is frequently observed in …

[HTML][HTML] The development of mesenchymal stem cell therapy in the present, and the perspective of cell-free therapy in the future

Y Watanabe, A Tsuchiya, S Terai - Clinical and molecular …, 2021 - ncbi.nlm.nih.gov
Cirrhosis is a chronic condition that can lead to liver failure. Currently, the viable option for
decreasing mortality is liver transplantation. However, transplant surgery is highly invasive …

Role of the gut–liver axis in liver inflammation, fibrosis, and cancer: a special focus on the gut microbiota relationship

N Ohtani, N Kawada - Hepatology communications, 2019 - journals.lww.com
The gut and the liver are anatomically and physiologically connected, and this “gut–liver
axis” exerts various influences on liver pathology. The gut microbiota consists of various …