Fundamental challenges and opportunities for preparative supercritical fluid chromatography

G Guiochon, A Tarafder - Journal of Chromatography A, 2011 - Elsevier
The use of supercritical fluids as mobile phases in chromatography was suggested nearly
fifty years ago. In spite of some major potential advantages, this mode of chromatography …

High-temperature liquid chromatography

T Greibrokk, T Andersen - Journal of Chromatography A, 2003 - Elsevier
The present state of the active use of elevated temperatures in liquid chromatography is
reviewed, including the effects on retention, selectivity and efficiency. Separations in …

Effects of high pressure in liquid chromatography

M Martin, G Guiochon - Journal of Chromatography A, 2005 - Elsevier
All the experimental parameters that the chromatographers are used to consider as constant
(the column length and its diameter, the particle size, the column porosities, the phase ratio …

Sense and nonsense of high-temperature liquid chromatography

S Heinisch, JL Rocca - Journal of Chromatography A, 2009 - Elsevier
High-temperature liquid chromatography (HTLC) is recognized today as a valuable
technique in reversed-phase high-performance liquid chromatography (RP-HPLC). Column …

Effect of temperature in reversed phase liquid chromatography

D Guillarme, S Heinisch, JL Rocca - Journal of Chromatography A, 2004 - Elsevier
The high temperature liquid chromatography (HTLC) reveals interesting chromatographic
properties but even now, it misses some theoretical aspects concerning the influence of high …

The limits of the separation power of unidimensional column liquid chromatography

G Guiochon - Journal of Chromatography A, 2006 - Elsevier
The practical limit of the separation power of HPLC depends on time, money, and skill. That
is it depends on the time available for the analysis, on the quality and performance of the …

Critical contribution of nonlinear chromatography to the understanding of retention mechanism in reversed-phase liquid chromatography

F Gritti, G Guiochon - Journal of Chromatography A, 2005 - Elsevier
The retention of most compounds in RPLC proceeds through a combination of several
independent mechanisms. We review a series of recent studies made on the behavior of …

Influence of frictional heating on temperature gradients in ultra-high-pressure liquid chromatography on 2.1 mm ID columns

A de Villiers, H Lauer, R Szucs, S Goodall… - … of Chromatography A, 2006 - Elsevier
The effects of viscous heat dissipation on some important HPLC parameters, such as
efficiency (N) and retention factors (k), using 2.1 mm columns at pressures up to 1000bar …

[图书][B] Handbook of HPLC

D Corradini, E Eksteen, R Eksteen, P Schoenmakers… - 1998 - taylorfrancis.com
Delineating its usage in separation, purification and detection processes across a variety of
disciplines, from industry to applied research, this work discusses the principles, techniques …

Adsorption mechanism in RPLC. Effect of the nature of the organic modifier

F Gritti, G Guiochon - Analytical chemistry, 2005 - ACS Publications
The adsorption isotherms of phenol and caffeine were acquired by frontal analysis on two
different adsorbents, Kromasil-C18 and Discovery-C18, with two different mobile phases …