The extended autonomic system, dyshomeostasis, and COVID-19

DS Goldstein - Clinical Autonomic Research, 2020 - Springer
The pandemic viral illness COVID-19 is especially life-threatening in the elderly and in those
with any of a variety of chronic medical conditions. This essay explores the possibility that …

Cardiac innervation and sudden cardiac death

K Fukuda, H Kanazawa, Y Aizawa, JL Ardell… - Circulation …, 2015 - Am Heart Assoc
Afferent and efferent cardiac neurotransmission via the cardiac nerves intricately modulates
nearly all physiological functions of the heart (chronotropy, dromotropy, lusitropy, and …

Clinical neurocardiology defining the value of neuroscience‐based cardiovascular therapeutics

K Shivkumar, OA Ajijola, I Anand… - The Journal of …, 2016 - Wiley Online Library
The autonomic nervous system regulates all aspects of normal cardiac function, and is
recognized to play a critical role in the pathophysiology of many cardiovascular diseases. As …

[HTML][HTML] Regulation of breathing and autonomic outflows by chemoreceptors

PG Guyenet - Comprehensive Physiology, 2014 - ncbi.nlm.nih.gov
Lung ventilation fluctuates widely with behavior but arterial PCO 2 remains stable. Under
normal conditions, the chemoreflexes contribute to PaCO 2 stability by producing small …

Developing the catecholamines hypothesis for the acute exercise-cognition interaction in humans: Lessons from animal studies

T McMorris - Physiology & behavior, 2016 - Elsevier
The catecholamines hypothesis for the acute exercise-cognition interaction in humans fails
to adequately explain the interaction between peripherally circulating catecholamines and …

Fasting-activated ventrolateral medulla neurons regulate T cell homing and suppress autoimmune disease in mice

L Wang, M Cheng, Y Wang, J Chen, F Xie… - Nature …, 2024 - nature.com
Dietary fasting markedly influences the distribution and function of immune cells and exerts
potent immunosuppressive effects. However, the mechanisms through which fasting …

Effect of acute hypoxia on cognition: A systematic review and meta-regression analysis

T McMorris, BJ Hale, M Barwood, J Costello… - Neuroscience & …, 2017 - Elsevier
A systematic meta-regression analysis of the effects of acute hypoxia on the performance of
central executive and non-executive tasks, and the effects of the moderating variables …

Vagus nerve stimulation activates two distinct neuroimmune circuits converging in the spleen to protect mice from kidney injury

S Tanaka, C Abe, SBG Abbott… - Proceedings of the …, 2021 - National Acad Sciences
Acute kidney injury is highly prevalent and associated with high morbidity and mortality, and
there are no approved drugs for its prevention and treatment. Vagus nerve stimulation (VNS) …

Neuronal networks in hypertension: recent advances

PG Guyenet, RL Stornetta, GMPR Souza… - …, 2020 - Am Heart Assoc
Neurogenic hypertension is associated with excessive sympathetic nerve activity to the
kidneys and portions of the cardiovascular system. Here we examine the brain regions that …

C1 neurons mediate a stress-induced anti-inflammatory reflex in mice

C Abe, T Inoue, MA Inglis, KE Viar, L Huang, H Ye… - Nature …, 2017 - nature.com
C1 neurons, located in the medulla oblongata, mediate adaptive autonomic responses to
physical stressors (for example, hypotension, hemorrhage and presence of …