The daily removal of billions of apoptotic cells in the human body via the process of
efferocytosis is essential for homeostasis. To allow for this continuous efferocytosis, rapid …

The clearance of apoptotic cells by professional and non-professional phagocytes—a
process termed 'efferocytosis'—is essential for the maintenance of tissue homeostasis …

Gram-negative bacteremia is a devastating public health threat, with high mortality in
vulnerable populations and significant costs to the global economy. Concerningly, rates of …

Efferocytosis is the effective clearance of apoptotic cells by professional and non-
professional phagocytes. The process is mechanically different from other forms of …

Pneumonia is inflammation in the lungs, which is usually caused by an infection. The
symptoms of pneumonia can vary from mild to life-threatening, where severe illness is often …

Since the discovery of cell apoptosis, other gene-regulated cell deaths are gradually
appreciated, including pyroptosis, ferroptosis, and necroptosis. Necroptosis is, so far, one of …

Interleukins (ILs) are signaling molecules that are crucial in regulating immune responses
during infectious diseases. Pro-inflammatory ILs contribute to the activation and recruitment …

Infections with bacterial pathogens often results in the initiation of programmed cell death as
part of the host innate immune defense, or as a bacterial virulence strategy. Induction of host …

Emergency myelopoiesis (EM) is a hematopoietic response against systemic infections that
quickly supplies innate immune cells. As lymphopoiesis is strongly suppressed during EM …

Highlights•Obligate and some facultative intracellular bacterial pathogens inhibit
apoptosis.•Bacteria inhibit apoptosis by disrupting ROS generation or mitochondrial …