There is increasing evidence that the brain relies on a set of canonical neural computations,
repeating them across brain regions and modalities to apply similar operations to different …

Schizophrenia is a complex neuropsychiatric disorder that is associated with persistent
psychosocial disability in affected individuals. Although studies of schizophrenia have …

Context Schizophrenia remains a highly disabling disorder, but the specific determinants
and pathways that lead to functional impairment are not well understood. It is not known …

Many risk genes interact synergistically to produce schizophrenia and many
neurotransmitter interactions have been implicated. We have developed a circuit-based …

1. After 50 years of antipsychotic drug development focused on the dopamine D2 receptor,
schizophrenia remains a chronic, disabling disorder for most affected individuals. 2. Studies …

Cognitive impairment is a core feature of schizophrenia and a major contributor to poor
functional outcomes. Methods for assessment of cognitive dysfunction in schizophrenia are …

Schizophrenia is a severe mental disorder associated with a characteristic constellation of
symptoms and neurocognitive deficits. At present, etiological mechanisms remain relatively …

Recently, a great deal of interest has arisen in resting state fMRI as a measure of tonic brain
function in clinical populations. Most studies have focused on the examination of temporal …

Schizophrenia is a serious mental disorder that affects up to 1% of the population worldwide.
As of yet, neurochemical mechanisms underlying schizophrenia remain unknown. To date …

Visual perception is one of the basic tools for exploring the world. However, in
schizophrenia, this modality is disrupted. So far, there has been no clear answer as to …