Background and aims Cannabis is the most widely used illicit substance globally. In this
systematic review, we examined the prevalence and trends of cannabis use and cannabis …

Drug use is an increasing global public health concern. We reviewed the prevalence and
patterns of drug use, drug use disorders, and the extent of treatment services in 21 countries …

Neuropathic pain, a disease of the somatosensory nervous system, afflicts many individuals
and adequate management with current pharmacotherapies remains elusive. The …

Background Opioid drug prescription (ODP) and opioid-related mortality (ORM) have
increased in Spain. However, their relationship is complex, as ORM is registered without …

Increasing illicit drug use is one of the main problems in most countries or societies.
Monitoring heavy metals and trace elements in this vulnerable group seems to be …

Background The old people population is increasing worldwide. Along with their increasing
population, an increase in elder abuse cases is predicted. Elder abuse is a neglected …

Tramadol is a widely prescribed painkiller around the world. As a synthetic opioid, it offers a
valuable substitute for morphine and its derivatives in African countries. However, the …

Tramadol is a synthetic opioid with centrally acting analgesic activity that alleviates
moderate to severe pain and treats withdrawal symptoms of the other opioids. Like other …

Background There has been a marked growth in methadone maintenance treatment (MMT)
in Iran in the past two decades with positive health outcomes. We conducted a systematic …

Background In the past few years, there has been an expanding global interest in the
problem of substance use. A variety of studies conducted within the past decade have …