When Folkman first suggested a theory about the association between angiogenesis and
tumor growth in 1971, the hypothesis of targeting angiogenesis to treat cancer was formed …

Gene electrotransfer is a powerful method of DNA delivery offering several medical
applications, among the most promising of which are DNA vaccination and gene therapy for …

Glioblastoma stem cells (GSCs) are subpopulations of tumor-initiating cells responsible for
glioblastoma (GBM) tumorigenesis and recurrence. Dual inhibition of vascular endothelium …

Tumor vessels can provide oxygen and nutrition for solid tumor tissue, create abnormal
tumor microenvironment (TME), and play a vital role in the development, immune escape …

Tumor-targeted drug delivery has the potential to improve therapeutic efficacy and mitigate
non-specific toxicity of anticancer drugs. However, current drug delivery approaches rely on …

Poor availability in deep-seated solid tumors is a significant challenge that limits the
effectiveness of currently used anticancer drugs. Approaches that can specifically enhance …

A nanocomposite hydrogel with photocrosslinkable micro-porous networks and a nanoclay
component was successfully prepared to control the release of growth factor-rich stem cell …

Anticancer therapies are often compromised by nonspecific effects and challenged by
tumour environments' inherent physicochemical and biological characteristics. Often …

Many recently discovered therapeutic proteins exert their main function in the nucleus, thus
requiring both efficient uptake and correct intracellular targeting. Chitosan nanoparticles …

Despite improvements in the early diagnosis, prognosis and therapeutic strategies for
gastric cancer (GC), human GC remains one of the most frequently diagnosed malignant …