Context processing and the neurobiology of post-traumatic stress disorder

I Liberzon, JL Abelson - Neuron, 2016 - cell.com
Progress in clinical and affective neuroscience is redefining psychiatric illness as
symptomatic expression of cellular/molecular dysfunctions in specific brain circuits. Post …

To predict, prevent, and manage post-traumatic stress disorder (PTSD): a review of pathophysiology, treatment, and biomarkers

GI Al Jowf, ZT Ahmed, RA Reijnders, L de Nijs… - International journal of …, 2023 - mdpi.com
Post-traumatic stress disorder (PTSD) can become a chronic and severely disabling
condition resulting in a reduced quality of life and increased economic burden. The disorder …

PTSD psychotherapy outcome predicted by brain activation during emotional reactivity and regulation

GA Fonzo, MS Goodkind, DJ Oathes… - American Journal of …, 2017 - Am Psychiatric Assoc
Objective: Exposure therapy is an effective treatment for posttraumatic stress disorder
(PTSD), but many patients do not respond. Brain functions governing treatment outcome are …

Intranasal oxytocin normalizes amygdala functional connectivity in posttraumatic stress disorder

SBJ Koch, M van Zuiden, L Nawijn, JL Frijling… - …, 2016 - nature.com
The neuropeptide oxytocin (OT) has been suggested as a promising pharmacological agent
for medication-enhanced psychotherapy in posttraumatic stress disorder (PTSD) because of …

[HTML][HTML] Dysregulation of inflammation, neurobiology, and cognitive function in PTSD: an integrative review

MM Quinones, AM Gallegos, FV Lin… - Cognitive, Affective, & …, 2020 - Springer
Compelling evidence from animal and human research suggest a strong link between
inflammation and posttraumatic stress disorder (PTSD). Furthermore, recent findings support …

Association of childhood maltreatment with interpersonal distance and social touch preferences in adulthood

A Maier, C Gieling, L Heinen-Ludwig… - American journal of …, 2020 - Am Psychiatric Assoc
Objective: Childhood maltreatment is a major risk factor for psychopathology associated with
interpersonal problems in adulthood, but the etiological pathways involved are still unclear …

Intranasal oxytocin administration dampens amygdala reactivity towards emotional faces in male and female PTSD patients

SBJ Koch, M van Zuiden, L Nawijn, JL Frijling… - …, 2016 - nature.com
Post-traumatic stress disorder (PTSD) is a disabling psychiatric disorder. As a substantial
part of PTSD patients responds poorly to currently available psychotherapies …

A predictive coding account of value-based learning in PTSD: Implications for precision treatments

A Putica, KL Felmingham, MI Garrido… - Neuroscience & …, 2022 - Elsevier
While there are a number of recommended first-line interventions for posttraumatic stress
disorder (PTSD), treatment efficacy has been less than ideal. Generally, PTSD treatment …

The need to take a staging approach to the biological mechanisms of PTSD and its treatment

AC McFarlane, E Lawrence-Wood, M Van Hooff… - Current psychiatry …, 2017 - Springer
Despite the substantial body of neurobiological research, no specific drug target has been
developed to treat PTSD and there are substantial limitations with the available …

The molecular biology of susceptibility to post-traumatic stress disorder: highlights of epigenetics and epigenomics

GI Al Jowf, C Snijders, BPF Rutten, L de Nijs… - International journal of …, 2021 - mdpi.com
Exposure to trauma is one of the most important and prevalent risk factors for mental and
physical ill-health. Excessive or prolonged stress exposure increases the risk of a wide …