Brønsted-Acid-Catalyzed Friedel–Crafts Reaction and Electrocyclization Cascade of Indoles with α-Functionalized Carbonyls

L Tan, T Xu, X Zhang, J Luo, X Xiao, L Li… - Organic …, 2023 - ACS Publications
Reported here is an efficient Friedel–Crafts-type reaction followed by electrocyclization
cascade under an air atmosphere, employing readily available building blocks as starting …

Gold-Catalyzed Cascade Reaction of 2-Alkynyl Aryl Azides with Enecarbamates for Direct Synthesis of α-(3-Indolyl) ketones

JM Xie, YL Zhu, YM Fu, CF Zhu, LJ Cheng… - Organic …, 2023 - ACS Publications
α-(3-Indolyl) ketones are essential building blocks for the generation of biologically active
molecules. We described a new method for the direct assembly of α-(3-indolyl) ketones …

Molecular iodine-catalyzed selective C-3 benzylation of indoles with benzylic alcohols: a greener approach toward benzylated indoles

P Bhattacharjee, U Bora - ACS omega, 2019 - ACS Publications
Iodine-catalyzed selective C-3 benzylation of indoles with benzylic alcohols is developed.
The reaction proceeds with molecular iodine as the catalyst under ligand-, metal-, and base …

Silver-catalyzed radical arylphosphorylation of unactivated alkenes: synthesis of 3-phosphonoalkyl indolines

D Liang, D Ge, Y Lv, W Huang, B Wang… - The Journal of Organic …, 2018 - ACS Publications
A silver-catalyzed phosphorylation/cyclization cascade of N-allyl anilines was developed,
allowing direct access to 3-phosphonoalkyl indolines, which were previously obtainable …

Phosphomolybdic acid as a bifunctional catalyst for Friedel–Crafts type dehydrative coupling reaction

GP Yang, D Dilixiati, T Yang, D Liu… - Applied …, 2018 - Wiley Online Library
Phosphomolybdic acid (H3PMo12O40) was found to be a bifunctional catalyst for C─ C
bond formation via the dehydrative reaction of diarylmethanols with various nucleophiles …

Iron‐Catalyzed exo‐Selective Synthesis of Cyanoalkyl Indolines via Cyanoisopropylarylation of Unactivated Alkenes

Y Li, Y Chang, Y Li, C Cao, J Yang… - Advanced Synthesis …, 2018 - Wiley Online Library
An iron‐catalyzed cyanoalkylation using azobisisobutyronitrile (AIBN) is reported. With
unactivated double bond as the radical acceptor, N‐allyl anilines underwent …

Synthesis of CF3CH2-Containing Indolines by Transition-Metal-Free Aryltrifluoromethylation of Unactivated Alkenes

D Liang, Q Dong, P Xu, Y Dong, W Li… - The Journal of Organic …, 2018 - ACS Publications
With an unactivated double bond as the radical acceptor, allyl amines underwent a metal-
free trifluoromethylation/cyclization cascade with CF3SO2Na (Langlois' reagent), affording …

A Brønsted Acid Catalyzed Cascade Reaction for the Conversion of Indoles to α‐(3‐Indolyl) Ketones by Using 2‐Benzyloxy Aldehydes

A Banerjee, MS Maji - Chemistry–A European Journal, 2019 - Wiley Online Library
A Brønsted acid catalyzed, operationally simple, scalable route to several functionalized α‐
(3‐indolyl) ketones has been developed and the long‐standing regioisomeric issue has …

Straight access to highly fluorescent angular indolocarbazoles via merging Au-and Mo-catalysis

F Martínez-Lara, A Suárez, S Suárez-Pantiga… - Organic Chemistry …, 2020 - pubs.rsc.org
A straightforward and efficient synthesis of the two less explored types of indolocarbazoles
has been developed. Two different processes for the carbazole nucleus preparation, a gold …

N-heterocyclic carbene and photocatalyst-catalyzed rapid access to indole ketones via radical C (sp 3)–H acylation

G Nie, T Tu, T Liao, D Liu, W Ye, SC Ren - Green Chemistry, 2024 - pubs.rsc.org
The direct C (sp3)–H functionalization reactions enable the development of green and
streamlined synthetic routes for structurally complex molecules by circumventing the pre …