Abstract Proksee (https://proksee. ca) provides users with a powerful, easy-to-use, and
feature-rich system for assembling, annotating, analysing, and visualizing bacterial …

The study of the respiratory microbiome has entered a multi-omic era. Through integrating
different omic data types such as metagenome, metatranscriptome, metaproteome …

It has become clear in recent years that anti-phage defense systems cluster non-randomly
within bacterial genomes in so-called “defense islands”. Despite serving as a valuable tool …

Bacteria use a diverse arsenal of anti-phage immune systems, including CRISPR-Cas and
restriction enzymes. Recent advances in anti-phage system discovery and annotation tools …

Real-time genomics through nanopore sequencing holds the promise of fast antibiotic
resistance prediction directly in the clinical setting. However, concerns about the accuracy of …

In contrast to the many reports of successful cases of personalized bacteriophage therapy,
randomized controlled trials of non-personalized bacteriophage products did not bring the …

Horizontal gene transfer (HGT) and gene duplication are often considered as separate
mechanisms driving the evolution of new functions. However, the mobile genetic elements …

Horizontal gene transfer accelerates microbial evolution. The marine picocyanobacterium
Prochlorococcus exhibits high genomic plasticity, yet the underlying mechanisms are …

As hotspots for the dissemination of antibiotic resistance genes (ARGs), wastewater
treatment plants (WWTPs) have attracted global attention. However, there lacks a sufficient …

Antibiotic resistance poses a significant threat to global health, and the microbe-rich
activated sludge environment may contribute to the dissemination of antibiotic resistance …