[HTML][HTML] Sepsis-associated acute kidney injury: consensus report of the 28th Acute Disease Quality Initiative workgroup

A Zarbock, MK Nadim, P Pickkers, H Gomez… - Nature Reviews …, 2023 - nature.com
Sepsis-associated acute kidney injury (SA-AKI) is common in critically ill patients and is
strongly associated with adverse outcomes, including an increased risk of chronic kidney …

[HTML][HTML] Acute kidney injury in the critically ill: an updated review on pathophysiology and management

P Pickkers, M Darmon, E Hoste, M Joannidis… - Intensive care …, 2021 - Springer
Acute kidney injury (AKI) is now recognized as a heterogeneous syndrome that not only
affects acute morbidity and mortality, but also a patient's long-term prognosis. In this …

[HTML][HTML] Signaling pathways and intervention therapies in sepsis

Y Zhang, B Ning - Signal Transduction and Targeted Therapy, 2021 - nature.com
Sepsis is defined as life-threatening organ dysfunction caused by dysregulated host
systemic inflammatory and immune response to infection. Over decades, advanced …

[HTML][HTML] Acute kidney injury from sepsis: current concepts, epidemiology, pathophysiology, prevention and treatment

S Peerapornratana, CL Manrique-Caballero… - Kidney international, 2019 - Elsevier
Sepsis-associated acute kidney injury (S-AKI) is a frequent complication of the critically ill
patient and is associated with unacceptable morbidity and mortality. Prevention of S-AKI is …

Sepsis associated acute kidney injury

JT Poston, JL Koyner - Bmj, 2019 - bmj.com
Sepsis is defined as organ dysfunction resulting from the host's deleterious response to
infection. One of the most common organs affected is the kidneys, resulting in sepsis …

Current concepts and advances in biomarkers of acute kidney injury

Y Wen, CR Parikh - Critical reviews in clinical laboratory sciences, 2021 - Taylor & Francis
Despite advancements in standardizing the criteria for acute kidney injury (AKI), its definition
remains based on changes in serum creatinine and urinary output that do not specifically …

Targeting acute kidney injury in COVID-19

JA Kellum, JWO van Till… - Nephrology Dialysis …, 2020 - academic.oup.com
Abstract As of 15 August 2020, Coronavirus disease 2019 (COVID-19) has been reported
in> 21 million people world-wide and is responsible for more than 750,000 deaths. The …

[HTML][HTML] Acute kidney injury

JA Kellum, P Romagnani, G Ashuntantang… - Nature reviews Disease …, 2021 - nature.com
Acute kidney injury (AKI) is defined by a sudden loss of excretory kidney function. AKI is part
of a range of conditions summarized as acute kidney diseases and disorders (AKD), in …

[HTML][HTML] Alkaline phosphatase: an old friend as treatment target for cardiovascular and mineral bone disorders in chronic kidney disease

M Haarhaus, G Cianciolo, S Barbuto, G La Manna… - Nutrients, 2022 - mdpi.com
Alkaline phosphatase (ALP) is an evolutionary conserved enzyme and widely used
biomarker in clinical practice. Tissue-nonspecific alkaline phosphatase (TNALP) is one of …

[HTML][HTML] Restrictive fluid management versus usual care in acute kidney injury (REVERSE-AKI): a pilot randomized controlled feasibility trial

ST Vaara, M Ostermann, L Bitker, A Schneider… - Intensive care …, 2021 - Springer
Purpose We compared a restrictive fluid management strategy to usual care among critically
ill patients with acute kidney injury (AKI) who had received initial fluid resuscitation. Methods …