Over the past two decades, multidisciplinary investigations into the development of
nanoparticles for medical applications have continually increased. However, nanoparticles …

Cancer immunotherapy is a therapeutic strategy to inhibit tumor growth and metastasis by
intervening in the immune response process. Strategies applied to cancer immunotherapy …

In clinical settings, cancer vaccines as monotherapies have displayed limited success
compared to other cancer immunotherapeutic treatments. Nanoscale formulations have the …

The goal of this research was to study the effect of polyanhydride chemistry on the immune
response induced by a prophylactic cancer vaccine based on biodegradable polyanhydride …

Many factors affect vaccine efficacy. One of the most salient is the frequency and intervals of
vaccine administration. In this study, we assessed the vaccine administration modality for a …

Triple-negative breast cancer (TNBC) is an immune-enriched subset of breast cancer that
has recently demonstrated clinical responsiveness to combinatorial immunotherapy …

The primary objective of this study was to enhance the antitumor efficacy of a model cancer
vaccine through co-delivery of pentaerythritol lipid A (PELA), an immunological adjuvant …

Leptospirosis is a debilitating infectious disease that detrimentally affects both animals and
humans; therefore, disease prevention has become a high priority to avoid high incidence …

Vaccines have been successful at preventing a range of diseases including diphtheria,
polio, whooping cough, measles and tetanus; whereby incidences of such diseases are now …