Meniscus repair and regeneration: a systematic review from a basic and translational science perspective

J Twomey-Kozak, C Jayasuriya - Clinics in sports medicine, 2020 - pmc.ncbi.nlm.nih.gov
Meniscus injuries are among the most common athletic injuries and result in functional
impairment in the knee. Repair is crucial for pain relief and prevention of degenerative joint …

Orthobiologics for bone healing

JG Calcei, SA Rodeo - Clinics in sports medicine, 2019 - sportsmed.theclinics.com
In all subspecialties of orthopedic surgery, bone healing is an important process that must
be appreciated and understood. Specifically, in sports medicine orthopedic surgery, bone …

Infrapatellar fat pad mesenchymal stromal cell–derived exosomes accelerate tendon-bone healing and intra-articular graft remodeling after anterior cruciate ligament …

J Xu, Z Ye, K Han, T Zheng, T Zhang… - … American journal of …, 2022 - journals.sagepub.com
Background: Exosomes derived from mesenchymal stromal cells (MSCs) reportedly
enhance the healing process. However, no studies have investigated the effect of exosomes …

Platelet-rich plasma in meniscal repair: does augmentation improve surgical outcomes?

JW Griffin, MM Hadeed, BC Werner… - Clinical Orthopaedics …, 2015 - journals.lww.com
Background Increased contact stresses after meniscectomy have led to an increased focus
on meniscal preservation strategies to prevent articular cartilage degeneration. Platelet-rich …

Platelet-rich plasma reduces failure risk for isolated meniscal repairs but provides no benefit for meniscal repairs with anterior cruciate ligament reconstruction

JS Everhart, PA Cavendish… - … American journal of …, 2019 - journals.sagepub.com
Background: The effect of platelet-rich plasma (PRP) on the risk of meniscal repair failure is
unclear. Current evidence is limited to small studies without comparison between isolated …

Platelet-rich plasma for primary treatment of partial ulnar collateral ligament tears: MRI correlation with results

JB Deal, E Smith, W Heard… - … journal of sports …, 2017 - journals.sagepub.com
Background: Jobe revolutionized the treatment of medial ulnar collateral ligament (MUCL)
tears with his reconstruction technique. However, not all MUCL injuries require operative …

Multiple injections of leukoreduced platelet rich plasma reduce pain and functional impairment in a canine model of ACL and meniscal deficiency

JL Cook, PA Smith, CC Bozynski… - Journal of …, 2016 - Wiley Online Library
Platelet rich plasma (PRP) is used to treat many musculoskeletal disorders. We used a
canine model to determine the effects of multiple intra‐articular injections of leukoreduced …

Meniscal root tears: a silent epidemic

ME Cinque, J Chahla, G Moatshe… - British journal of sports …, 2018 - bjsm.bmj.com
Half of adults will experience knee pain at some point during their lives, resulting in
approximately 4 million primary care office visits in the USA annually. 1 The majority of these …

Combination of platelet-rich plasma and bone marrow mesenchymal stem cells enhances tendon–bone healing in a rabbit model of anterior cruciate ligament …

C Teng, C Zhou, D Xu, F Bi - Journal of Orthopaedic Surgery and Research, 2016 - Springer
Background The objective of this study was to investigate the potency of platelet-rich plasma
(PRP) combined with bone marrow mesenchymal stem cells (BMSCs) to promote tendon …

The current role of biologics for meniscus injury and treatment

ID Hutchinson, SA Rodeo - Current Reviews in Musculoskeletal Medicine, 2022 - Springer
Abstract Purpose of Review There is little doubt that the consensus has changed to favor
preservation of meniscal function where possible. Accordingly, the indications for meniscal …