Nanotechnology's frontier in combatting infectious and inflammatory diseases: prevention and treatment

Y Huang, X Guo, Y Wu, X Chen, L Feng, N Xie… - … and Targeted Therapy, 2024 - nature.com
Inflammation-associated diseases encompass a range of infectious diseases and non-
infectious inflammatory diseases, which continuously pose one of the most serious threats to …

Bioinspired polymer vesicles and membranes for biological and medical applications

CG Palivan, R Goers, A Najer, X Zhang, A Car… - Chemical society …, 2016 - pubs.rsc.org
Biological membranes play an essential role in living organisms by providing stable and
functional compartments, preserving cell architecture, whilst supporting signalling and …

Advancements in prophylactic and therapeutic nanovaccines

P Bhardwaj, E Bhatia, S Sharma, N Ahamad… - Acta Biomaterialia, 2020 - Elsevier
Vaccines activate suitable immune responses to fight against diseases but can possess
limitations such as compromised efficacy and immunogenic responses, poor stability, and …

[HTML][HTML] Biomimetic artificial organelles with in vitro and in vivo activity triggered by reduction in microenvironment

T Einfalt, D Witzigmann, C Edlinger, S Sieber… - Nature …, 2018 - nature.com
Despite tremendous efforts to develop stimuli-responsive enzyme delivery systems, their
efficacy has been mostly limited to in vitro applications. Here we introduce, by using an …

Promising nanomaterials in the fight against malaria

LN Borgheti-Cardoso, M San Anselmo… - Journal of Materials …, 2020 - pubs.rsc.org
For more than one hundred years, several treatments against malaria have been proposed
but they have systematically failed, mainly due to the occurrence of drug resistance in part …

Coating nanoparticles with cell membranes for targeted drug delivery

W Gao, L Zhang - Journal of drug targeting, 2015 - Taylor & Francis
Targeted delivery allows drug molecules to preferentially accumulate at the sites of action
and thus holds great promise to improve therapeutic index. Among various drug-targeting …

Mimicking cellular signaling pathways within synthetic multicompartment vesicles with triggered enzyme activity and induced ion channel recruitment

S Thamboo, A Najer, A Belluati… - Advanced Functional …, 2019 - Wiley Online Library
Subcellular compartmentalization of cells, a defining characteristic of eukaryotes, is
fundamental for the fine tuning of internal processes and the responding to external stimuli …

Dynamics of membrane proteins within synthetic polymer membranes with large hydrophobic mismatch

F Itel, A Najer, CG Palivan, W Meier - Nano letters, 2015 - ACS Publications
The functioning of biological membrane proteins (MPs) within synthetic block copolymer
membranes is an intriguing phenomenon that is believed to offer great potential for …

[HTML][HTML] Biopores/membrane proteins in synthetic polymer membranes

M Garni, S Thamboo, CA Schoenenberger… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Background Mimicking cell membranes by simple models based on the reconstitution of
membrane proteins in lipid bilayers represents a straightforward approach to understand …

Biomolecules turn self-assembling amphiphilic block co-polymer platforms into biomimetic interfaces

S Yorulmaz Avsar, M Kyropoulou, S Di Leone… - Frontiers in …, 2019 - frontiersin.org
Biological membranes constitute an interface between cells and their surroundings and form
distinct compartments within the cell. They also host a variety of biomolecules that carry out …