Antimicrobial cationic peptides are ubiquitous in nature and are thought to be a component
of the first line of defense against infectious agents. It is widely believed that the killing …

Methicillin-resistant Staphylococcus aureus (MRSA), are the most frequent cause of sepsis,
which urgently demanding new drugs for treating infection. Two homologous insect CSαβ …

Listeria monocytogenes, which causes serious foodborne infections and public health
problems worldwide, is one of the most important foodborne pathogens. Linalool has been …

Defensins are a family of broad-spectrum antimicrobial peptides found abundantly in the
cytoplasmic granules of mammalian neutrophils and Paneth cells of the small intestine …

Violacein, violet pigment produced by Chromobacterium violaceum, has attracted much
attention recently due to its pharmacological properties including antibacterial activity. The …

Background Pseudomonas aeruginosa is a Gram-negative pathogen that frequently causes
life-threatening infections in immunocompromised patients. We previously showed that …

Changes in bacterial ultrastructure after antibiotic exposure and during the postantibiotic
effect (PAE) have been demonstrated by electron microscopy (EM). However, EM is …

Pharmacodynamics (PD) considers the relationship between drug exposure and effect. The
two factors that have been used to distinguish the PD behaviors of antimicrobials are the …

The influence of half-life on the postantibiotic effect (PAE) of tobramycin against
Pseudomonas aeruginosa and Staphylococcus aureus was investigated during one dosing …

Studies on bacterial metabolism during the postantibiotic effect (PAE) period are limited but
might provide insight into the nature of the PAE. We evaluated the rate of DNA synthesis in …