Background: Since the cornea is responsible for transmitting and focusing light into the eye,
injury or pathology affecting any layer of the cornea can cause a detrimental effect on visual …

The corneal endothelium is the posterior monolayer of cells that are responsible for
maintaining overall transparency of the avascular corneal tissue via pump function. These …

Human-induced pluripotent stem cells (hiPSCs) provide a personalized approach to study
conditions and diseases including those of the eye that lack appropriate animal models to …

Dysfunction of the corneal endothelium (CE) resulting from progressive cell loss leads to
corneal oedema and significant visual impairment. Current treatments rely upon donor …

Cornea is an avascular and transparent tissue that focuses light on retina. Cornea is
supported by the corneal‐endothelial layer through regulation of hydration homeostasis …

The cornea is a multi-layered structure which allows fine refraction and provides both
resistance to external insults and adequate transparency. The corneal endothelium ensures …

The corneal endothelium plays a key role in maintaining corneal transparency. Its
dysfunction is currently treated with penetrating or lamellar keratoplasty. Advanced cell …

The treatment of corneal endothelial dysfunction has experienced a revolutionary change in
the past decades with the emergence of endothelial keratoplasty techniques: descemet …

Corneal blindness is the fourth leading cause of visual impairment. Of specific interest is
blindness due to a dysfunctional corneal endothelium which can only be treated by …

The determination of potential transplantable substrates and substitution cells for corneal
endothelium transplantation may compensate for the shortage of cornea donors …