Atherosclerosis and inflammation: insights from the theory of general pathological processes

E Gusev, A Sarapultsev - International Journal of Molecular Sciences, 2023 - mdpi.com
Recent advances have greatly improved our understanding of the molecular mechanisms
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …

Immunomodulating effects of epigallocatechin-3-gallate from green tea: mechanisms and applications

M Pae, D Wu - Food & function, 2013 - pubs.rsc.org
Consuming green tea or its active ingredient, epigallocatechin-3-gallate (EGCG), has been
shown consistently to benefit the healthy functioning of several body systems. In the immune …

M. tuberculosis-initiated human mannose receptor signaling regulates macrophage recognition and vesicle trafficking by FcRγ-Chain, Grb2, and SHP-1

MVS Rajaram, E Arnett, AK Azad, E Guirado, B Ni… - Cell reports, 2017 - cell.com
Despite its prominent role as a C-type lectin (CTL) pattern recognition receptor, mannose
receptor (MR, CD206)-specific signaling molecules and pathways are unknown. The MR is …

Physiological and pathogenic role of scavenger receptors in humans

EY Gusev, NV Zotova, YA Zhuravleva, VA Chereshnev - 2020 - elar.urfu.ru
The scavenger receptors (SRs)) include> 30 different molecules structurally classified into
11 classes (A to L). They are expressed mostly on stromal macrophages, and their …

Физиологическая и патогенетическая роль рецепторов-мусорщиков у человека

ЕЮ Гусев, НВ Зотова, ЮА Журавлева… - Медицинская …, 2020 - cyberleninka.ru
Рецепторы мусорщики SR (scavenger receptor) включают более 30 отдельных
представителей, разделенных по структурному принципу на 11 классов (AL). Они …

GRP75 modulates oncogenic Dbl-driven endocytosis derailed via the CHIP-mediated ubiquitin degradation pathway

X Niu, L Su, S Qi, Z Gao, Q Zhang, S Zhang - Cell death & disease, 2018 - nature.com
Chaperone-assisted proteasome degradation of oncogenic protein acts as an upstream
signal controlling tumorigenesis and progression. The understanding of the co-regulation of …

GRP75 upregulates clathrin-independent endocytosis through actin cytoskeleton reorganization mediated by the concurrent activation of Cdc42 and RhoA

H Chen, Z Gao, C He, R Xiang… - Experimental cell …, 2016 - Elsevier
Therapeutic macromolecules are internalized into the cell by either clathrin-mediated
endocytosis (CME) or clathrin-independent endocytosis (CIE). Although some chaperone …

[PDF][PDF] Extracellular Heat Shock Proteins as a Natural Protector of Cells and Organisms: A Review of Recent Studies

K Nishizawa, M Nishizawa - Ann Biomed Res, 2018 - gen.g.dgdg.jp
The heat shock protein (HSP) family consists of molecular chaperones that are evolutionary
preserved from prokaryotes and mammals. The extracellular HSPs are now known to be …

Extracellular Heat Shock Proteins as Stress Communication Signals

A De Maio - Heat Shock Proteins in the Immune System, 2018 - Springer
Intercellular communication is a fundamental process necessary to maintain homeostasis
and to mount an orchestrated response to stress. Although heat shock proteins (HSP) play a …

[PDF][PDF] Investigating the effect of soluble BiP on human regulatory T cell frequency and function

AM Gazali - 2015 - academia.edu
Abstract Binding Immunoglobulin Protein (BiP) is a member of the HSP70 family and is
currently being used in clinical trials to treat rheumatoid arthritis. Soluble BiP has been …