Epidermal growth factor, innovation and safety

JE Caussa, EH Vila - Medicina Clínica (English Edition), 2015 - Elsevier
Bioidentical recombinant human epidermal growth factor (rhEGF) is available in
concentrations and purity suitable for therapeutic use in long time stable formulations …

Eyelash trichomegaly: a systematic review of acquired and congenital aetiologies of lengthened lashes

DM Hutchison, A Duffens, K Yale, A Park… - Journal of the …, 2022 - Wiley Online Library
Long eyelashes have been popularized and many commercially available products exist to
achieve eyelash growth as a desired cosmetic effect. Eyelash trichomegaly may be induced …

[HTML][HTML] Inhibition of Shh signaling through MAPK activation controls chemotherapy-induced alopecia

IS Haslam, GX Zhou, GJ Xie, X Teng, XL Ao… - Journal of Investigative …, 2021 - Elsevier
Chemotherapy-induced hair loss (alopecia)(CIA) remains a major unsolved problem in
clinical oncology. CIA is often considered to be a consequence of the antimitotic and …

Arctiin blocks hydrogen peroxide-induced senescence and cell death though microRNA expression changes in human dermal papilla cells

S Bae, KM Lim, HJ Cha, IS An, JP Lee, KS Lee… - Biological research, 2014 - Springer
Background Accumulating evidence indicates that reactive oxygen species (ROS) are an
important etiological factor for the induction of dermal papilla cell senescence and hair loss …

α-tocopherol as a selective modulator of toxicogenic damage induced by antineoplastic agents cyclophosphamide and doxorubicin

VA de Oliveira, ANR Monteiro Fernandes… - Journal of Toxicology …, 2023 - Taylor & Francis
The aim of this study was to determine the oxidative/antioxidative effects, modulatory and
selective potential of α-tocopherol (vitamin E) on antineoplastic drug-induced toxicogenetic …

[HTML][HTML] Testing chemotherapeutic agents in the feather follicle identifies a selective blockade of cell proliferation and a key role for sonic hedgehog signaling in …

G Xie, H Wang, Z Yan, L Cai, G Zhou, W He… - Journal of Investigative …, 2015 - Elsevier
Chemotherapeutic agents induce complex tissue responses in vivo and damage normal
organ functions. Here we use the feather follicle to investigate details of this damage …

A newly discovered linkage between proteoglycans and hair biology: decorin acts as an anagen inducer

S Inui, S Itami - Experimental Dermatology, 2014 - Wiley Online Library
Proteoglycans have been suggested to play pivotal roles in hair biology. Decorin is a
prototypical member of the small leucine‐rich proteoglycan family, which is involved in …

Computational drug discovery in chemotherapy-induced alopecia via text mining and biomedical databases

N Zhang, W Xu, S Wang, Y Qiao, X Zhang - Clinical therapeutics, 2019 - Elsevier
Purpose Chemotherapy-induced alopecia (CIA) is a common and often stressful adverse
effect associated with chemotherapy. CIA can cause more psychosocial pressure in patients …

The Inhibition of Oxidative Stress-Mediated Cell Apoptosis by the Caspase Inhibitor (S)-3-((S)-2-(6-(2, 3-dihydrobenzo [b][1, 4] dioxin-6-yl)-1-oxoisoindolin-2-yl) …

B Park, D Kim, Y Lee, S Choi, HD Park, S Lee, J Hwang - Cosmetics, 2024 - mdpi.com
Alopecia is traditionally viewed as androgen-dependent, but emerging evidence has
implicated oxidative stress in the pathogenesis of hair loss. Current treatments for alopecia …

[PDF][PDF] An overview of management of drug-induced hair and nail disorders

S Patel, A Tosti - Clinical Practice, 2014 - pcds.org.uk
The diagnosis and management of drug-induced hair and nail disorders in the clinic
presents a unique challenge for the physician. Not only must the physician recognize the …